RNA catalyses nuclear pre-mRNA splicing - Wikidata - awgldk - TriplyDB

RNA catalyses nuclear pre-mRNA splicing

RNA catalyses nuclear pre-mRNA splicing

http://www.wikidata.org/entity/Q34382976

about

The rise of regulatory RNA The nuts and bolts of the endogenous spliceosome Group II introns: versatile ribozymes and retroelements New Perspectives on DNA and RNA Triplexes As Effectors of Biological Activity CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast Functional roles of DExD/H-box RNA helicases in Pre-mRNA splicing RNA-Binding Proteins: Splicing Factors and Disease The architecture of the spliceosomal U4/U6.U5 tri-snRNP.Core structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolution Molecular targets of aspirin and cancer prevention.Cryo-EM structure of the spliceosome immediately after branching The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome The persistent contributions of RNA to eukaryotic gen(om)e architecture and cellular function Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation.RNA-RNA interactions and pre-mRNA mislocalization as drivers of group II intron loss from nuclear genomes.Methods for comprehensive experimental identification of RNA-protein interactions Evolution of group II introns From General Aberrant Alternative Splicing in Cancers and Its Therapeutic Application to the Discovery of an Oncogenic DMTF1 Isoform.Crystal structure of a eukaryotic group II intron lariat Mechanisms and Regulation of Alternative Pre-mRNA Splicing Evidence for a group II intron-like catalytic triplex in the spliceosome Design and Experimental Evolution of trans-Splicing Group I Intron Ribozymes.GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo.Spliceozymes: ribozymes that remove introns from pre-mRNAs in trans.The spliceosomal PRP19 complex of trypanosomes Mobile Bacterial Group II Introns at the Crux of Eukaryotic Evolution Spliceosome assembly in the absence of stable U4/U6 RNA pairing.Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.Mechanistic Studies Reveal Similar Catalytic Strategies for Phosphodiester Bond Hydrolysis by Protein-only and RNA-dependent Ribonuclease P NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.Circular RNAs with hammerhead ribozymes encoded in eukaryotic genomes: The enemy at home.An active site rearrangement within the Tetrahymena group I ribozyme releases nonproductive interactions and allows formation of catalytic interactions.Probing the kinetic and thermodynamic consequences of the tetraloop/tetraloop receptor monovalent ion-binding site in P4-P6 RNA by smFRET.Effect of Zn2+ binding and enzyme active site on the transition state for RNA 2'-O-transphosphorylation interpreted through kinetic isotope effects.Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly.Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution A Two-Way Street: Regulatory Interplay between RNA Polymerase and Nascent RNA Structure.Substrate-assisted mechanism of RNP disruption by the spliceosomal Brr2 RNA helicase.

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RNA catalyses nuclear pre-mRNA splicing

http://www.wikidata.org/entity/Q34382976

description

2013 nî lūn-bûn

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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

RNA catalyses nuclear pre-mRNA splicing

@ast

RNA catalyses nuclear pre-mRNA splicing

@en

RNA catalyses nuclear pre-mRNA splicing

@nl

type

label

RNA catalyses nuclear pre-mRNA splicing

@ast

RNA catalyses nuclear pre-mRNA splicing

@en

RNA catalyses nuclear pre-mRNA splicing

@nl

prefLabel

RNA catalyses nuclear pre-mRNA splicing

@ast

RNA catalyses nuclear pre-mRNA splicing

@en

RNA catalyses nuclear pre-mRNA splicing

@nl

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RNA catalyses nuclear pre-mRNA splicing

@en

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Jonathan P Staley

http://www.w3.org/2001/XMLSchema#string

Joseph A Piccirilli

http://www.w3.org/2001/XMLSchema#string

Jun Lu

http://www.w3.org/2001/XMLSchema#string

Nan-Sheng Li

http://www.w3.org/2001/XMLSchema#string

Nicole Tuttle

http://www.w3.org/2001/XMLSchema#string

Prakash Koodathingal

http://www.w3.org/2001/XMLSchema#string

Qing Dai

http://www.w3.org/2001/XMLSchema#string

Sebastian M Fica

http://www.w3.org/2001/XMLSchema#string

Thaddeus Novak

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The antiquity of RNA-based evolution

A general two-metal-ion mechanism for catalytic RNA

The structural basis of ribosome activity in peptide bond synthesis

Crystal Structure of a Self-Spliced Group II Intron

Visualizing Group II Intron Catalysis through the Stages of Splicing

Crystal structure of Prp8 reveals active site cavity of the spliceosome

Structure of the yeast U2/U6 snRNA complex

A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation

Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components.

The Prp19p-associated complex in spliceosome activation.

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229-234

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scholarly article

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10.1038/NATURE12734

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7475

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503

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