Pharmacogenetics of cancer therapy: getting personal - Wikidata - awgldk - TriplyDB

Pharmacogenetics of cancer therapy: getting personal

Pharmacogenetics of cancer therapy: getting personal

http://www.wikidata.org/entity/Q34386321

about

Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core Drug methylation in cancer therapy: lessons from the TPMT polymorphism Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine Association of ITPA genotype with event-free survival and relapse rates in children with acute lymphoblastic leukemia undergoing maintenance therapy Disequilibrium mapping of a quantitative-trait locus in an expanding population.Pharmacokinetically guided dose adjustment of 5-fluorouracil: a rational approach to improving therapeutic outcomes.Review and meta-analysis of systematic searches for uniparental disomy (UPD) other than UPD 15.Murine pharmacogenomics: using the mouse to understand the genetics of drug therapy.Pharmacogenomics: marshalling the human genome to individualise drug therapy Azathioprine: current status and future considerations.Cancer pharmacogenomics: SNPs, chips, and the individual patient.Development and implementation of a pharmacist-managed clinical pharmacogenetics service.Watson and Crick 50 years on. From double helix to pharmacogenomics.Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment Japanese single nucleotide polymorphism database for 267 possible drug-related genes.Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy.Pharmacogenetics and diseases of the colon.ITPA (inosine triphosphate pyrophosphatase): from surveillance of nucleotide pools to human disease and pharmacogenetics Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia.Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status.Pharmacogenomics of pediatric acute lymphoblastic leukemia.Pharmacogenetics in dermatology: a patient-centered update.Thiopurine metabolite testing in inflammatory bowel disease.cDNA microarray analysis of vascular gene expression after nitric oxide donor infusions in rats: implications for nitrate tolerance mechanisms.Nanomedicine Faces Barriers.Influence of thiopurine methyltransferase gene polymorphism on Egyptian children with acute lymphoblastic leukaemia.

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Pharmacogenetics of cancer therapy: getting personal

http://www.wikidata.org/entity/Q34386321

description

1998 nî lūn-bûn

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1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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1998 թվականի հուլիսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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Pharmacogenetics of cancer therapy: getting personal

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American Journal of Human Genetics

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Pharmacogenetics of cancer therapy: getting personal

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E Y Krynetski

http://www.w3.org/2001/XMLSchema#string

W E Evans

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P2860

Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase

Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians

Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity

Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms

Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism

Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

The purine path to chemotherapy.

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11-16

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10.1086/301941

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1

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