High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands
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Functional MAPT haplotypes: bridging the gap between genotype and neuropathologyMutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 betaPin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?Frontotemporal lobar degeneration: old knowledge and new insight into the pathogenetic mechanisms of tau mutationsPhenotypic Heterogeneity of Monogenic Frontotemporal DementiaDisrupting self-assembly and toxicity of amyloidogenic protein oligomers by "molecular tweezers" - from the test tube to animal modelsInvited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimagingClosing the tau loop: the missing tau mutation.Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-β1Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's diseaseThe effect of a DeltaK280 mutation on the unfolded state of a microtubule-binding repeat in TauConserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family MembersReduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutationsPreventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.A new family with frontotemporal dementia with intronic 10+3 splice site mutation in the tau gene: neuropathology and molecular effects.Role of MAPT mutations and haplotype in frontotemporal lobar degeneration in Northern FinlandHDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulinInhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease.Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies.Fibrillogenesis of tau: insights from tau missense mutations in FTDP-17.Single mutations in tau modulate the populations of fibril conformers through seed selection.Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q.Characteristics of frontotemporal dementia patients with a Progranulin mutation.Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases.The cytoskeleton in neurodegenerative diseases.The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner.Hereditary frontotemporal dementia caused by Tau gene mutations.Presenile dementia syndromes: an update on taxonomy and diagnosis.Competition for microtubule-binding with dual expression of tau missense and splice isoforms.Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells.Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles.Interactions between Aβ and mutated Tau lead to polymorphism and induce aggregation of Aβ-mutated tau oligomeric complexesA novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function.The acetylation of tau inhibits its function and promotes pathological tau aggregation.Altered functional connectivity in asymptomatic MAPT subjects: a comparison to bvFTDA network of RNA and protein interactions in Fronto Temporal Dementia.Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca(++) dysregulationMedical management of frontotemporal dementias: the importance of the caregiver in symptom assessment and guidance of treatment strategiesFounder mutations among the Dutch.
P2860
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P2860
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
High prevalence of mutations i ...... al dementia in the Netherlands
@ast
High prevalence of mutations i ...... al dementia in the Netherlands
@en
High prevalence of mutations i ...... al dementia in the Netherlands
@nl
type
label
High prevalence of mutations i ...... al dementia in the Netherlands
@ast
High prevalence of mutations i ...... al dementia in the Netherlands
@en
High prevalence of mutations i ...... al dementia in the Netherlands
@nl
prefLabel
High prevalence of mutations i ...... al dementia in the Netherlands
@ast
High prevalence of mutations i ...... al dementia in the Netherlands
@en
High prevalence of mutations i ...... al dementia in the Netherlands
@nl
P2093
P2860
P356
P1476
High prevalence of mutations i ...... al dementia in the Netherlands
@en
P2093
Hasegawa M
Hillebrand M
Niermeijer MF
P2860
P304
P356
10.1086/302256
P407
P577
1999-02-01T00:00:00Z