Competition for microtubule-binding with dual expression of tau missense and splice isoforms.
about
New Features about Tau Function and DysfunctionAcetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survivalGenotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tauTau isoform regulation is region- and cell-specific in mouse brain.Roles of tau protein in health and disease.Tau mutants bind tubulin heterodimers with enhanced affinity.Genetics of frontotemporal lobar degenerationFragmentation of the Golgi apparatus induced by the overexpression of wild-type and mutant human tau forms in neurons.Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE.Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau.Tau alternative splicing and frontotemporal dementia.Tau exon 10 alternative splicing and tauopathiesStructural principles of tau and the paired helical filaments of Alzheimer's disease.The role of tau in neurodegenerationAmyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases.The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule.The power and richness of modelling tauopathies in Drosophila.Tau protein and adult hippocampal neurogenesis.Regulation of alternative splicing of tau exon 10.Cell-based Models To Investigate Tau Aggregation.Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17.Tau and neurodegenerative disease: the story so far.New routes in frontotemporal dementia drug discovery.Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis.Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndromeMyotonic dystrophy expanded CUG repeats disturb the expression and phosphorylation of tau in PC12 cells.Dysregulation of Microtubule Stability Impairs Morphofunctional Connectivity in Primary Neuronal Networks.Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress.Up-regulation of casein kinase 1ε is involved in tau pathogenesis in Alzheimer's disease.The formation of tau pathological phospho-epitopes in the axon is prevented by the dephosphorylation of selective sites in primary hippocampal neurons over-expressing human tau.Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35. Implications for Alzheimer's disease.Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons.Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.On-chip microtubule gliding assay for parallel measurement of tau protein species.Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.La lunga attesa: towards a molecular approach to neuroimaging and therapeutics in Alzheimer's disease.Selective deposition of mutant tau in the FTDP-17 brain affected by the P301L mutation.Tau gene mutations and their effects.
P2860
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P2860
Competition for microtubule-binding with dual expression of tau missense and splice isoforms.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Competition for microtubule-bi ...... missense and splice isoforms.
@ast
Competition for microtubule-bi ...... missense and splice isoforms.
@en
Competition for microtubule-bi ...... missense and splice isoforms.
@nl
type
label
Competition for microtubule-bi ...... missense and splice isoforms.
@ast
Competition for microtubule-bi ...... missense and splice isoforms.
@en
Competition for microtubule-bi ...... missense and splice isoforms.
@nl
prefLabel
Competition for microtubule-bi ...... missense and splice isoforms.
@ast
Competition for microtubule-bi ...... missense and splice isoforms.
@en
Competition for microtubule-bi ...... missense and splice isoforms.
@nl
P2860
P356
P1476
Competition for microtubule-bi ...... missense and splice isoforms.
@en
P2860
P304
P356
10.1091/MBC.12.1.171
P577
2001-01-01T00:00:00Z