Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide.
about
Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamateReversible Competitive α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Constraints in the Acyl Side Chain: Orally Active, Long-Acting AnalgesicsPresence and regulation of the endocannabinoid system in human dendritic cellsThe discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).Regulation of gonadotropin-releasing hormone secretion by cannabinoids.Functional disassociation of the central and peripheral fatty acid amide signaling systems.Endocannabinoids and neuroprotection.Mechanisms of non-opioid analgesics beyond cyclooxygenase enzyme inhibition.Fatty acid synthase as a factor required for exercise-induced cognitive enhancement and dentate gyrus cellular proliferation.Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerolClickable, photoreactive inhibitors to probe the active site microenvironment of fatty acid amide hydrolase().Anandamide: an update.Discovery of a potent, selective, and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesicsEndocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain.Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase.Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates.Pharmacology of traumatic brain injury: where is the "golden bullet"?Optimization of alpha-ketooxazole inhibitors of fatty acid amide hydrolase.Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries.Factors and pathways involved in capacitation: how are they regulated?Fatty acid amide signaling molecules.Endocannabinoids and neuropathic pain: focus on neuron-glia and endocannabinoid-neurotrophin interactions.What failed BIA 10-2474 Phase I clinical trial? Global speculations and recommendations for future Phase I trials.Polyunsaturated fatty acids and endocannabinoids in health and disease.N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase.Neurosecretion competence. A comprehensive gene expression program identified in PC12 cells.Mutations in Arabidopsis fatty acid amide hydrolase reveal that catalytic activity influences growth but not sensitivity to abscisic acid or pathogens.Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol.Association between single nucleotide polymorphisms in the cannabinoid receptor gene (CNR1) and impulsivity in southwest California Indians.Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems.Molecular identification of a functional homologue of the mammalian fatty acid amide hydrolase in Arabidopsis thaliana.Rare genetic variants in the endocannabinoid system genes CNR1 and DAGLA are associated with neurological phenotypes in humans.Endocannabinoid-related compounds in gastrointestinal diseases.What failed BIA 10–2474 Phase I clinical trial? Global speculations and recommendations for future Phase I trials.N-aryl 2-aryloxyacetamides as a new class of fatty acid amide hydrolase (FAAH) inhibitors.Endocannabinoids and Food Intake: Newborn Suckling and Appetite Regulation in Adulthood
P2860
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P2860
Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@ast
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@en
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@nl
type
label
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@ast
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@en
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@nl
prefLabel
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@ast
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@en
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@nl
P2093
P921
P1476
Fatty acid amide hydrolase: bi ...... oylethanolamide, and oleamide.
@en
P2093
P304
P356
10.1016/S0006-2952(01)00712-2
P407
P577
2001-09-01T00:00:00Z