Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids

Item
http://www.wikidata.org/entity/Q34394212
Multi-Target Directed Donepezil-Like Ligands for Alzheimer's DiseaseDrug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening MethodologiesMonoaminergic and Histaminergic Strategies and Treatments in Brain DiseasesASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy.The proof-of-concept of ASS234: Peripherally administered ASS234 enters the central nervous system and reduces pathology in a male mouse model of Alzheimer disease.Cinnamaldehyde, Cinnamic Acid, and Cinnamyl Alcohol, the Bioactives of Cinnamomum cassia Exhibit HDAC8 Inhibitory Activity: An In vitro and In silico Study.A perspective on multi-target drug discovery and design for complex diseases.Alzheimer: A decade of drug design. Why molecular topology can be an extra edge.Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database.Crystal structure, DFT calculations and evaluation of 2-(2-(3,4-dimethoxyphenyl)ethyl)isoindoline-1,3-dione as AChE inhibitor.
P2860

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids

Item
http://www.wikidata.org/entity/Q34394212
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
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Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
@en
Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
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type
label
Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
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Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
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Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
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prefLabel
Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
@ast
Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
@en
Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
@nl
P1433
P1476
P2093
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P1433
P1476
Multipotent cholinesterase/mon ...... ovel donepezil-pyridyl hybrids
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P2093
P2860
P304
P31
P356
P407
P478
P50
P577
P698
P921
P932