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Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and designMolecular immunolabeling with recombinant single-chain variable fragment (scFv) antibodies designed with metal-binding domainsZinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cellsThe design of Förster (fluorescence) resonance energy transfer (FRET)-based molecular sensors for Ran GTPaseMolecular mechanism of pancreatic tumor metastasis inhibition by Gd@C82(OH)22 and its implication for de novo design of nanomedicineDesign of protein-ligand binding based on the molecular-mechanics energy modelFrom molecular to macroscopic via the rational design of a self-assembled 3D DNA crystalMolecular docking as a popular tool in drug design, an in silico travelMolecular docking and structure-based drug design strategiesMoving molecular targeted drug therapy towards personalized medicine: issues related to clinical trial designProtein-carbohydrate interactions studied by NMR: from molecular recognition to drug designCurrent immunological and molecular tools for leptospirosis: diagnostics, vaccine design, and biomarkers for predicting severityMolecular design of fluorescent probes and development of novel fluorescent mother compoundsBiomarkers of treatment toxicity in combined-modality cancer therapies with radiation and systemic drugs: study design, multiplex methods, molecular networksThe genetic basis and expanding role of molecular analysis in the diagnosis, prognosis, and therapeutic design for myelodysplastic syndromesFibrin-based biomaterials: modulation of macroscopic properties through rational design at the molecular level.Capturing the embryonic stages of self-assembly - design rules for molecular computation.Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands.Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1BDesign, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilusMolecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664Preorganization of molecular binding sites in designed diiron proteinsDesign of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studiesRational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptinMolecular design of heteroprotein assemblies providing a bionanocup as a chemical reactorSolution NMR Structure of a Designed Metalloprotein and Complementary Molecular Dynamics RefinementMinimal Pharmacophoric Elements and Fragment Hopping, an Approach Directed at Molecular Diversity and Isozyme Selectivity. Design of Selective Neuronal Nitric Oxide Synthase InhibitorsThe importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinaseThe role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and DIodine Atoms: A New Molecular Feature for the Design of Potent Transthyretin Fibrillogenesis InhibitorsA designed chimeric cyanovirin-N homolog lectin: Structure and molecular basis of sucrose bindingDiscovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug designDesign, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins (αRep) based on thermostable HEAT-like repeatsStructure of RavA MoxR AAA+ protein reveals the design principles of a molecular cage modulating the inducible lysine decarboxylase activityMolecular design principles underlying β-strand swapping in the adhesive dimerization of cadherinsDesign strategies to target crystallographic waters applied to the Hsp90 molecular chaperoneDetermining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: a study for antiparasitic drug designIntroducing lasso peptides as molecular scaffolds for drug design: engineering of an integrin antagonistDecoding the molecular design principles underlying Ca(2+) binding to βγ-crystallin motifsDesign, Synthesis, and Molecular Modeling of Novel Pyrido[2,3- d ]pyrimidine Analogues As Antifolates; Application of Buchwald–Hartwig Aminations of Heterocycles
P921
Q21090062-05D1B983-3E95-40D4-A86A-7D5F33E83695Q24531284-0160C867-2D4C-413E-A627-C763A562FB33Q24535831-215BDC28-5C31-4E7E-AD47-1588D31C30E4Q24595055-3169FA9E-04F8-467A-8B67-22586C1B7CC1Q24633644-BE0F3D22-31B4-43E4-9D19-D0C211BBF509Q24651388-8C187424-9C71-45B8-9588-C7311286165AQ24651456-6562EB5D-4303-4387-A633-AE41C57DF2D1Q26743663-9180C81F-CA6E-48A1-B371-0A803241DE35Q26800097-AB7232BA-C4CD-4578-A52A-328510403E83Q26830525-0FE913DE-833D-4DF6-8D85-9F6B184ACC5FQ26849619-2FF09F77-2494-4EC7-B529-797E965E7206Q26863215-B900F543-E2F2-4066-9621-015229D3410CQ26865515-21FE5890-1A2B-4333-93BA-F30BB769D20EQ26991945-F230BA4D-D24F-4283-8485-F0833C85A62EQ26995222-2D50003D-84FF-4AF2-B0A0-37ABD39DEE9AQ27003215-9DABB0F3-8D27-4ADD-9408-D75901109576Q27309012-142F49BB-8DB5-4AD6-A938-B43B867BC2EAQ27325455-E79A0116-471B-4D49-B077-76665A698FB5Q27622003-F6F0D233-B3A8-46D6-8773-161A2CDAD8B7Q27629491-18416071-9E8C-4AFC-A765-9FE211C1F08DQ27636691-9F41CE98-04CF-4AFD-923A-1DFD6BF74843Q27640786-4647AAAB-EEF6-4369-B5DD-AB85FAD03AAEQ27641742-EE68F04F-444C-4CC2-ADE4-A332717C0B37Q27644443-4396972C-9670-4F38-95F9-516CCB66DAE6Q27649387-98B2C05D-D36B-4634-80CB-75A9D83CEF35Q27649856-3C40FBB4-52FD-4727-A321-A3CBB0E20782Q27649995-82608819-A325-4C85-8CE1-2D91F93A3F7EQ27652725-CDC9AFB5-A5FC-4EE5-AFD6-303532187F17Q27652837-B17495B9-BADE-404D-9BBF-46396869301FQ27653350-DBF459EA-BB61-4757-A56A-B4EA076F1EA4Q27656745-EB827C1C-6D60-4436-A2BC-1ABE4C01AAD7Q27663623-7F0D6840-6DE5-4FF4-9F51-3455FC1A7B6AQ27664852-A5B24E95-D8F1-41F7-896B-CCCEBEE69411Q27666334-D12AB4B9-5F5B-473A-BEE3-8EE98819F099Q27667852-D4A1DEF5-3665-45DC-9D13-18CA5DC5C108Q27668006-C2E52D7F-F392-4BFE-8803-9C940EE7F74CQ27670984-DFCF8C1E-13FE-4BC7-9507-C59D060A7A66Q27671423-C3217D32-3DC2-460B-8E8D-CA23CEDE27C1Q27675651-0A1F67C6-E03C-410C-8A4B-70CF9E415C52Q27677848-EBE0256D-70C6-494A-AD31-CFC171514DAC
P921
description
subfield of chemistry
@en
name
molecular design
@en
molekula fasonado
@eo
type
label
molecular design
@en
molekula fasonado
@eo
prefLabel
molecular design
@en
molekula fasonado
@eo