NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers. - Wikidata - awgldk - TriplyDB

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.

http://www.wikidata.org/entity/Q34394696

about

Notch Signaling in Neuroendocrine Tumors Super-enhancers: Asset management in immune cell genomes Emerging concepts of epigenetic dysregulation in hematological malignancies The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes EBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1 dbSUPER: a database of super-enhancers in mouse and human genome Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers.Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control.Notch signaling regulates antigen sensitivity of naive CD4+ T cells by tuning co-stimulation.Repression of Ccr9 transcription in mouse T lymphocyte progenitors by the Notch signaling pathway.Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility.The role of Notch receptors in transcriptional regulation Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation.Long-Range Chromosome Interactions Mediated by Cohesin Shape Circadian Gene Expression.SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers.Network analysis of gene essentiality in functional genomics experiments.Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β.Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case.Small genomic insertions form enhancers that misregulate oncogenes Novel function of MDA-9/Syntenin (SDCBP) as a regulator of survival and stemness in glioma stem cells.The role of epigenetic mechanisms in Notch signaling during development.Epigenetics in T-cell acute lymphoblastic leukemia.Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases.Epstein-Barr virus nuclear protein EBNA3C directly induces expression of AID and somatic mutations in B cells.Targeting the Notch Pathway to Prevent Rejection.Genome-wide identification and characterization of Notch transcription complex-binding sequence-paired sites in leukemia cells.Oncogenic Notch signaling in T-cell and B-cell lymphoproliferative disorders.Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia.The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-κB and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells.The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.Super-Enhancer-Driven Transcriptional Dependencies in Cancer.The Varied Roles of Notch in Cancer.Aberrant activation of the GIMAP enhancer by oncogenic transcription factors in T-cell acute lymphoblastic leukemia.Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation.

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P2860

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.

http://www.wikidata.org/entity/Q34394696

description

2013 nî lūn-bûn

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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

NOTCH1-RBPJ complexes drive ta ...... eractions with superenhancers.

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NOTCH1-RBPJ complexes drive ta ...... eractions with superenhancers.

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NOTCH1-RBPJ complexes drive ta ...... eractions with superenhancers.

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NOTCH1-RBPJ complexes drive ta ...... eractions with superenhancers.

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NOTCH1-RBPJ complexes drive ta ...... eractions with superenhancers.

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NOTCH1-RBPJ complexes drive ta ...... eractions with superenhancers.

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PNAS.1315023111

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Proceedings of the National Academy of Sciences of the United States of America

P1476

NOTCH1-RBPJ complexes drive ta ...... eractions with superenhancers.

@en

P2093

Hongfang Wang

http://www.w3.org/2001/XMLSchema#string

Jon C Aster

http://www.w3.org/2001/XMLSchema#string

Len Taing

http://www.w3.org/2001/XMLSchema#string

Stephen C Blacklow

http://www.w3.org/2001/XMLSchema#string

Warren S Pear

http://www.w3.org/2001/XMLSchema#string

X Shirley Liu

http://www.w3.org/2001/XMLSchema#string

Yinling Joey Wong

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P2860

Model-based analysis of ChIP-Seq (MACS)

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

p300 acts as a transcriptional coactivator for mammalian Notch-1

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Combinatorial patterns of histone acetylations and methylations in the human genome

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

Super-enhancers in the control of cell identity and disease

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705-710

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scholarly article

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10.1073/PNAS.1315023111

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2

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111

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3896193

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