Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants. - Wikidata - awgldk - TriplyDB

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

http://www.wikidata.org/entity/Q34397259

about

CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biology Insulin-secreting β cells require a post-genomic concept Recent progress in genetic and epigenetic research on type 2 diabetes Transcriptional enhancers: functional insights and role in human disease Connecting SNPs in Diabetes: A Spatial Analysis of Meta-GWAS Loci The molecular clock as a metabolic rheostat Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion β-cell dysfunction: Its critical role in prevention and management of type 2 diabetes.The selection and function of cell type-specific enhancers Epigenetic Regulation of Islet Development and Regeneration Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network The genetic architecture of type 2 diabetes Integrative analysis of 111 reference human epigenomes Islet biology, the CDKN2A/B locus and type 2 diabetes risk.Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis Genetic and epigenetic variation in the lineage specification of regulatory T cells.Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.GENOME-WIDE INTERACTION WITH SELECTED TYPE 2 DIABETES LOCI REVEALS NOVEL LOCI FOR TYPE 2 DIABETES IN AFRICAN AMERICANS.Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants.Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line.The Pancreatic Islet Regulome Browser.A comparative analysis of human and mouse islet G-protein coupled receptor expression.Enhancers and chromatin structures: regulatory hubs in gene expression and diseases.Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.Minireview: mechanisms of growth hormone-mediated gene regulation.Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility.The Missing lnc(RNA) between the pancreatic β-cell and diabetes Genome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits.The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression.Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers.The pancreatic β cell: recent insights from human genetics.Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

http://www.wikidata.org/entity/Q34397259

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@ast

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@en

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@nl

type

label

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@ast

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@en

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@nl

prefLabel

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@ast

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@en

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@nl

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Nature Genetics

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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

@en

P2093

Ferenc Müller

http://www.w3.org/2001/XMLSchema#string

Ignasi Morán

http://www.w3.org/2001/XMLSchema#string

Inês Cebola

http://www.w3.org/2001/XMLSchema#string

Javier García-Hurtado

http://www.w3.org/2001/XMLSchema#string

Joan Ponsa-Cobas

http://www.w3.org/2001/XMLSchema#string

Miguel Angel Maestro

http://www.w3.org/2001/XMLSchema#string

Natalia Castro

http://www.w3.org/2001/XMLSchema#string

Takao Nammo

http://www.w3.org/2001/XMLSchema#string

Thierry Berney

http://www.w3.org/2001/XMLSchema#string

P2860

A user's guide to the encyclopedia of DNA elements (ENCODE)

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Model-based analysis of ChIP-Seq (MACS)

An integrated encyclopedia of DNA elements in the human genome

Rfx6 directs islet formation and insulin production in mice and humans

H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Histone H3K27ac separates active from poised enhancers and predicts developmental state

MafB is required for islet beta cell maturation

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136-143

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scholarly article

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10.1038/NG.2870

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P433

2

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46

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Lorenzo Piemonti

José Luis Gómez-Skarmeta

Francois Pattou

Carlos Gómez-Marín

Martijn van de Bunt

P577

2014-01-12T00:00:00Z

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259699443

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1028426177

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24413736

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type-2 diabetes

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3935450

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