Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
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Evidence for interaction between human PRUNE and nm23-H1 NDPKinaseNm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cellsTumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulationCrystal structure of human nucleoside diphosphate kinase A, a metastasis suppressorYNK1, the yeast homolog of human metastasis suppressor NM23, is required for repair of UV radiation- and etoposide-induced DNA damage.Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosisPuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE)Decoding Cellular Dynamics in Epidermal Growth Factor Signaling Using a New Pathway-Based Integration Approach for Proteomics and Transcriptomics Data.Drosophila awd, the homolog of human nm23, regulates FGF receptor levels and functions synergistically with shi/dynamin during tracheal development.Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migrationThe Nm23-H1 metastasis suppressor as a translational target.Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity.Cross-platform Comparison of Two Pancreatic Cancer PhenotypesNm23-H1: genetic alterations and expression patterns in tumor metastasis.Effects of body-resistance strengthening and tumor-suppressing granules on immune adhesion function of red blood cells and expression of metastasis protein CD44 in tumor cells of patients with esophageal carcinoma.Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic virusesMetastasis suppressor NME1 regulates melanoma cell morphology, self-adhesion and motility via induction of fibronectin expressionThe tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers.NME genes in epithelial morphogenesis.Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines.Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase.Altered gene and protein expression by Nm23-H1 in metastasis suppression.Awd, the homolog of metastasis suppressor gene Nm23, regulates Drosophila epithelial cell invasion.Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity.Characterization of the 3' --> 5' exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues.The glucocorticoid receptor signalling in breast cancer.Developmental function of Nm23/awd: a mediator of endocytosis.The Drosophila metastasis suppressor gene Nm23 homolog, awd, regulates epithelial integrity during oogenesis.Potential contributions of antimutator activity to the metastasis suppressor function of NM23-H1.Multiple mechanisms underlie metastasis suppressor function of NM23-H1 in melanoma.Protein-protein interactions: a mechanism regulating the anti-metastatic properties of Nm23-H1.Human nucleoside diphosphate kinase B (Nm23-H2) from melanoma cells shows altered phosphoryl transfer activity due to the S122P mutation.Nm23-H1 can induce cell cycle arrest and apoptosis in B cells.Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells.General and specific promotions of flagellar assembly by a flagellar nucleoside diphosphate kinase.Histidine to aspartate phosphotransferase activity of nm23 proteins: phosphorylation of aldolase C on Asp-319.nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP.A sensitive screening assay for secreted motility-stimulating factors.
P2860
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P2860
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@ast
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@en
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@nl
type
label
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@ast
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@en
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@nl
prefLabel
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@ast
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@en
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@nl
P2093
P2860
P356
P1476
Site-directed mutagenesis of n ...... human breast carcinoma cells.
@en
P2093
P2860
P304
25107-25116
P356
10.1074/JBC.271.41.25107
P407
P577
1996-10-01T00:00:00Z