Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
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Pharmacokinetics of dihydrocodeine and its active metabolite after single and multiple oral dosingDiclofenac does not interact with codeine metabolism in vivo: a study in healthy volunteersAnalgesic effects of codeine-6-glucuronide after intravenous administrationPharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquineDisposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers.Drug interactions and the statins.Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates.The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomesPopulation pharmacokinetics of nortriptyline during monotherapy and during concomitant treatment with drugs that inhibit CYP2D6--an evaluation with the nonparametric maximum likelihood method.Patient-controlled analgesia (PCA) with codeine for postoperative pain relief in ten extensive metabolisers and one poor metaboliser of dextromethorphanThe pharmacogenetics of analgesia: toward a genetically-based approach to pain management.Differential foetal development of the O- and N-demethylation of codeine and dextromethorphan in manA comparison of the pharmacokinetics of codeine and its metabolites in healthy Chinese and Caucasian extensive hydroxylators of debrisoquine.Interindividual and interethnic differences in the demethylation and glucuronidation of codeine.Infants and young children metabolise codeine to morphine. A study after single and repeated rectal administration.Perturbation of paracetamol urinary metabolic ratios by urine flow rate.Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone.Effects of ethanol on ethylmorphine metabolism in isolated rat hepatocytes: characterization by means of a multicompartmental model.Pharmacogenetics: the therapeutic drug monitoring of the future?Thebaine O-demethylation to oripavine: genetic differences between two rat strains.Pharmacogenetics: Part I.The human hepatic cytochromes P450 involved in drug metabolism.CYP induction-mediated drug interactions: in vitro assessment and clinical implications.Pharmacogenetics of opioids.Metabolism of antidepressant and neuroleptic drugs by cytochrome p450s: clinical and interethnic aspects.Overview of pharmacogenetics.Metabolism of drugs of abuse by cytochromes P450.Genetic polymorphism of sparteine/debrisoquine oxidation: a reappraisal.Prediction of xenobiotic metabolism by non-invasive methods.Genome technologies and personalized dental medicine.Emerging roles for brain drug-metabolizing cytochrome P450 enzymes in neuropsychiatric conditions and responses to drugs.Genetic differences in drug disposition.Clinical importance of hepatic cytochrome P450 in drug metabolism.Formation of morphine from codeine in Chinese subjects of different CYP2D6 genotypes.In vitro forecasting of drugs that may interfere with codeine bioactivation.Cytochrome-P450-dependent hydroxylation in cluster headache.Dihydrocodeine: a new opioid substrate for the polymorphic CYP2D6 in humans.Influence of the CYP2D6 polymorphism and hemodialysis on codeine disposition in patients with end-stage renal disease.Growth hormone replacement therapy induces codeine clearance.CYP2D6-inhibiting drugs and the increased risk of fall-related injuries due to newly initiated opioid treatment--a Swedish, register-based case-crossover study.
P2860
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P2860
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
description
1989 nî lūn-bûn
@nan
1989 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@ast
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@en
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@nl
type
label
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@ast
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@en
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@nl
prefLabel
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@ast
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@en
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@nl
P2093
P2860
P1476
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
@en
P2093
P2860
P304
P356
10.1111/J.1365-2125.1989.TB03556.X
P407
P577
1989-12-01T00:00:00Z