Calcium dysregulation, IP3 signaling, and Alzheimer's disease. - Wikidata - awgldk - TriplyDB

Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

http://www.wikidata.org/entity/Q34399955

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Synergy and Antagonism of Active Constituents of ADAPT-232 on Transcriptional Level of Metabolic Regulation of Isolated Neuroglial Cells Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment Long-term dantrolene treatment reduced intraneuronal amyloid in aged Alzheimer triple transgenic mice Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease.A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology.Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation.Workflow and methods of high-content time-lapse analysis for quantifying intracellular calcium signals.Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease.Inositol trisphosphate receptor Ca2+ release channels in neurological diseases.Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice.Novel mechanism of increased Ca2+ release following oxidative stress in neuronal cells involves type 2 inositol-1,4,5-trisphosphate receptors.General anesthetic isoflurane modulates inositol 1,4,5-trisphosphate receptor calcium channel opening.Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease Differential subcellular Ca2+ signaling in a highly specialized subpopulation of astrocytes.Presenilin-like GxGD membrane proteases have dual roles as proteolytic enzymes and ion channels.Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice.Analyzing and Quantifying the Gain-of-Function Enhancement of IP3 Receptor Gating by Familial Alzheimer's Disease-Causing Mutants in Presenilins.Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store.Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies.The pathogenesis of Alzheimers disease is it a lifelong "calciumopathy"?Alterations of some membrane transport proteins in Alzheimer's disease: role of amyloid beta-peptide.Impaired mitochondrial function due to familial Alzheimer's disease-causing presenilins mutants via Ca(2+) disruptions.Anesthesia, calcium homeostasis and Alzheimer's disease Intracellular calcium signalling in Alzheimer's disease Synapses, NMDA receptor activity and neuronal Aβ production in Alzheimer's disease.K(Ca)2 and k(ca)3 channels in learning and memory processes, and neurodegeneration.Network-wide dysregulation of calcium homeostasis in Alzheimer's disease.Dantrolene, a treatment for Alzheimer disease?Amyloid-beta-(1-42) increases ryanodine receptor-3 expression and function in neurons of TgCRND8 mice.Mitochondrial Regulatory Pathways in the Pathogenesis of Alzheimer's Disease.The Role of Presenilin in Protein Trafficking and Degradation-Implications for Metal Homeostasis.Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.IP3 receptor mutations and brain diseases in human and rodents.Neuronal calcium wave propagation varies with changes in endoplasmic reticulum parameters: a computer model.Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease.Rosuvastatin and thapsigargin modulate γ-secretase gene expression and APP processing in a human neuroglioma model.Enhanced ROS generation mediated by Alzheimer's disease presenilin regulation of InsP3R Ca2+ signaling.

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P2860

Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

http://www.wikidata.org/entity/Q34399955

description

2005 nî lūn-bûn

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2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2005 թվականի ապրիլին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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type

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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The Neuroscientist

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Calcium dysregulation, IP3 signaling, and Alzheimer's disease.

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Grace E Stutzmann

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P2860

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Neuronal calcium signaling

Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders.

Calcium, a signaling molecule in the endoplasmic reticulum?

Abnormal intracellular ca(2+)homeostasis and disease.

Mechanisms of Ca(2+)-dependent transcription.

Stores not just for storage. intracellular calcium release and synaptic plasticity.

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease

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110-115

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2

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15746379

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Alzheimer's disease