Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice. - Wikidata - awgldk - TriplyDB

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

http://www.wikidata.org/entity/Q34401495

about

Opa1 is required for proper mitochondrial metabolism in early development Nucleotide salvage deficiencies, DNA damage and neurodegeneration Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication Limited dCTP availability accounts for mitochondrial DNA depletion in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)Transgenic overexpression of ribonucleotide reductase improves cardiac performance.Increases in mitochondrial DNA content and 4977-bp deletion upon ATM/Chk2 checkpoint activation in HeLa cells.Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations Mechanisms of mitochondrial diseases.Ribonucleotide reductase subunit p53R2 regulates mitochondria homeostasis and function in KB and PC-3 cancer cells.Mitochondrial purine and pyrimidine metabolism and beyond.Fast and sensitive HPLC-MS/MS method for direct quantification of intracellular deoxyribonucleoside triphosphates from tissue and cells.Astrocytes: new players in progressive myoclonus epilepsy of Lafora type.Mutations defective in ribonucleotide reductase activity interfere with pollen plastid DNA degradation mediated by DPD1 exonuclease.

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P2860

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

http://www.wikidata.org/entity/Q34401495

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@ast

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@en

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@nl

type

label

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@ast

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@en

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@nl

prefLabel

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@ast

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@en

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@nl

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P1433

Nucleic Acids Research

P1476

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

@en

P2093

Anu Suomalainen

http://www.w3.org/2001/XMLSchema#string

Gerold Bepler

http://www.w3.org/2001/XMLSchema#string

Jennifer L Page

http://www.w3.org/2001/XMLSchema#string

Milla Lampinen

http://www.w3.org/2001/XMLSchema#string

Robert S Weiss

http://www.w3.org/2001/XMLSchema#string

Tomomi Ide

http://www.w3.org/2001/XMLSchema#string

P2860

Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder

p53 has a direct apoptogenic role at the mitochondria

A ribonucleotide reductase gene is a transcriptional target of p53 and p73

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA

Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy

Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

Similarity of human mitochondrial transcription factor 1 to high mobility group proteins

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

P304

8208-8218

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scholarly article

P356

10.1093/NAR/GKQ735

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P407

P433

22

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38

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Henna Tyynismaa

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2010-08-19T00:00:00Z

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P5875

45720798

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P698

20724444

http://www.w3.org/2001/XMLSchema#string

P921

mitochondrial DNA

P932

3001089

http://www.w3.org/2001/XMLSchema#string