Translocations involving anaplastic lymphoma kinase (ALK). - Wikidata - awgldk - TriplyDB

Translocations involving anaplastic lymphoma kinase (ALK).

Translocations involving anaplastic lymphoma kinase (ALK).

http://www.wikidata.org/entity/Q34405439

about

Stimulation of CD30 in anaplastic large cell lymphoma leads to production of nuclear factor-kappaB p52, which is associated with hyperphosphorylated Bcl-3 Evaluation of EML4-ALK fusion proteins in non-small cell lung cancer using small molecule inhibitors Primary systemic anaplastic large cell lymphoma in Korean adults: 11 years' experience at Asan Medical Center Nucleophosmin: from structure and function to disease development Aberrant activation of the hedgehog signaling pathway in malignant hematological neoplasms Second- and third-generation ALK inhibitors for non-small cell lung cancer Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA)Novel mRNA-containing cytoplasmic granules in ALK-transformed cells.Effect of single-chain antibody targeting of the ligand-binding domain in the anaplastic lymphoma kinase receptor.An orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis.Aberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilization Synergistic growth inhibition of anaplastic large cell lymphoma cells by combining cellular ALK gene silencing and a low dose of the kinase inhibitor U0126 Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung.Fusion of the SEC31L1 and ALK genes in an inflammatory myofibroblastic tumor.Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma Identification of C/EBPβ target genes in ALK+ anaplastic large cell lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation.Biological role of anaplastic lymphoma kinase in neuroblastoma.Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single 'hit' and cooperate in producing a mastocytosis-like disease in mice.Fibroblast growth factor receptor-Frs2α signaling is critical for nephron progenitors.Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell lymphoma Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.ALK a novel lymphoma-associated tumor antigen for vaccination strategies.Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging.What have we learnt from mouse models of NPM-ALK-induced lymphomagenesis?Anaplastic lymphoma kinase and its signalling molecules as novel targets in lymphoma therapy.Constitutive control of AKT1 gene expression by JUNB/CJUN in ALK+ anaplastic large-cell lymphoma: a novel crosstalk mechanism.Current progress of RNA aptamer-based therapeutics.Fusion tyrosine kinase mediated signalling pathways in the transformation of haematopoietic cells.ALK receptor activation, ligands and therapeutic targeting in glioblastoma and in other cancers.New therapeutic strategies in neuroblastoma: combined targeting of a novel tyrosine kinase inhibitor and liposomal siRNAs against ALK.Nucleophosmin: a versatile molecule associated with hematological malignancies.Diffuse large B-cell lymphoma: a heterogeneous group of non-Hodgkin lymphomas comprising several distinct clinicopathological entities.Predicting the outcome in non-Hodgkin lymphoma with molecular markers.The natural product avrainvillamide binds to the oncoprotein nucleophosmin.Anaplastic large cell lymphoma with primary involvement of skeletal muscle: a rare case report and review of the literature.Oncogenic mutations of ALK in neuroblastoma.

P2860

Q24316194-5BD35CF1-4A42-4687-AA00-0B2E2F1FBDE8 Q24595585-8F0E3440-69EC-4F2A-8722-87AC4AAD5BA0 Q24652793-D65717DE-1DBA-47CF-8F90-05C370272768 Q26739704-E4641C4E-A84D-4ECA-AA69-0227D57D1A66 Q26866139-DF7DF25D-F2D8-4490-ABA7-DBCCD8BFA9C6 Q28072496-66C4514B-1B56-4797-A740-2286F84C776B Q28214508-687DED6F-5AE1-4253-90D2-46BDC6D3EA15 Q28506804-E2583CAF-E768-44C3-B3A4-0F94778406EB Q28588852-3F73BD07-9C99-418B-9996-F32576F54767 Q30498700-3149645F-CD7F-47D4-9A3D-3D173F560224 Q33487136-A6CFA395-688E-4F50-B1ED-FA9773F76BC5 Q33588267-43032852-4B13-427C-AFA0-975DCA7930F0 Q33851681-17EC9585-6F53-4D1A-9C34-AA5D0D0D766B Q34057987-2894C7F8-2D42-44CA-BA90-B7A37F8F4E7E Q34349164-ECA6466F-2A9F-4838-903A-951F167D3935 Q34450749-8BAF4B71-F244-41A4-80C8-DE55095DFC6B Q34552993-EC13BE5D-C155-435D-A750-BA226C1AB65F Q34607749-F942DDDF-51A0-4EED-87B6-0BEFAE291613 Q34760541-3F9B4DE4-144B-492C-B5AB-E5B7D7FB6B95 Q35084934-91EEFAC6-90DF-487B-A3FD-18320740207F Q35131224-6A45482B-E4FD-4824-829C-1DC2AEAAAEC1 Q35169575-CBB5ADE5-BC2F-45CF-989F-DED55CD5344B Q35181459-A466A4F5-4CD9-43AC-8133-4E93E75C43B1 Q35285497-23F0C25F-8BC2-4074-87A1-7F2BE7ECB467 Q35575978-B089234D-60AD-46EB-A716-F530983D1FE1 Q35614635-D06B79C7-9098-4B38-9554-9C5DBDC77E12 Q35937929-E0A06B6A-F2DB-466E-BE0B-6C2D93C12F1F Q36132014-89BCDDA8-D788-4CBC-B982-613B66C26373 Q36158713-056C67EF-FA64-4DDC-99CA-60203A6106F1 Q36248978-E921E3B7-E441-43F4-9EB7-3F452886471F Q36365202-B8A695E3-78F1-43AD-A9D8-35550BCB4CBF Q36398134-1878917E-648C-4B2F-AC71-8EB32B8541F7 Q36477122-8ECBB325-45BD-474B-8008-BC55A93AD442 Q36557133-FE1715FC-E6FB-4218-864A-4A3532EF11AA Q36597677-5CE28BD3-F2CC-4855-9BDB-2C7FD5C8C1CD Q36622610-85904423-2F0A-4615-BB1F-5ADC741E2771 Q36780164-389B09DF-ABA7-44D8-B45E-4A5422C79382 Q36917895-124A98F5-F672-4E58-BC3B-2486063048CC Q37453264-60A93DCB-EB26-4BEC-9DE1-6F0EA30A9CC0 Q37825940-0D1BFB36-D076-4177-8D5F-F7CB9372E606

P2860

Translocations involving anaplastic lymphoma kinase (ALK).

http://www.wikidata.org/entity/Q34405439

description

2001 nî lūn-bûn

@nan

2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Translocations involving anaplastic lymphoma kinase (ALK).

@ast

Translocations involving anaplastic lymphoma kinase (ALK).

@en

Translocations involving anaplastic lymphoma kinase

@nl

type

label

Translocations involving anaplastic lymphoma kinase (ALK).

@ast

Translocations involving anaplastic lymphoma kinase (ALK).

@en

Translocations involving anaplastic lymphoma kinase

@nl

prefLabel

Translocations involving anaplastic lymphoma kinase (ALK).

@ast

Translocations involving anaplastic lymphoma kinase (ALK).

@en

Translocations involving anaplastic lymphoma kinase

@nl

P1433

Q34405439-97B09F97-BF31-4418-9ABA-12D147A6FF8B

P1476

Q34405439-9C550753-EFD1-4B5E-999F-66B9C7268AA7

P2093

Q34405439-4A973B57-8F3B-41BB-A7F0-CA19839A7AF2

Q34405439-7948D310-4030-4508-BEF4-C25AA5E24FB2

Q34405439-A717EBB8-8579-43C8-ADA7-04DFDB4DC1F5

P2860

Q34405439-13718749-CE5D-4EA3-AD2D-336E6ABAA84F

Q34405439-1593BCD8-537D-45B8-ACDA-42BC45D586B0

Q34405439-1621D2FA-415C-444D-8AEC-5BA467623461

Q34405439-18D2581C-A219-4AB9-89ED-C0D4FBE1C91F

Q34405439-1BDECDDC-DD1A-4FD2-8469-A59E40BBE63E

Q34405439-1D232EFF-F44A-47E9-A6F8-4C66A17F8F2E

Q34405439-1ED6F6F5-F493-439C-A609-0F749BDA49CD

Q34405439-1F438E50-5D64-4B04-B284-0392A5D82665

Q34405439-20F046D7-7B20-4A0B-9D4A-3A9694EBABD0

Q34405439-2330CA3E-44B4-4304-854A-720CD0AF2928

P2888

Q34405439-DD942187-F9B8-4C6E-B6EA-2FC79B2136FE

P304

Q34405439-5340D2EF-1C49-4BA9-8B42-A8341D0767CE

P31

Q34405439-A38486B4-A355-4D2C-8459-11419115BBBB

P356

Q34405439-C9E54A2E-4C2A-4943-BEBA-93A8B01B70CC

P407

Q34405439-CBA91236-C2D2-4C72-BCB7-7E402BD23A5C

P433

Q34405439-C09BCBE1-2ABE-4D39-AA90-0348E34C1418

P478

Q34405439-74CAC640-4C45-4941-AB19-615057FD4686

P577

Q34405439-8A82B361-93D2-41DE-88D3-B1E2872DC5CD

P6179

Q34405439-5BD6F5D8-B8BA-4C0C-80CF-DE73825B4B0F

P698

Q34405439-DFDC6909-D6C8-4947-9931-A26717D8DD57

P356

P1433

P1476

Translocations involving anaplastic lymphoma kinase (ALK).

@en

P2093

Bai RY

http://www.w3.org/2001/XMLSchema#string

Duyster J

http://www.w3.org/2001/XMLSchema#string

Morris SW

http://www.w3.org/2001/XMLSchema#string

P2860

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domain

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease

ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity

P2888

P304

5623-5637

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1204594

http://www.w3.org/2001/XMLSchema#string

P407

P433

40

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P577

2001-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1015440801

http://www.w3.org/2001/XMLSchema#string

P698

11607814

http://www.w3.org/2001/XMLSchema#string