Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis
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Cloning, expression and nuclear localization of human NPM3, a member of the nucleophosmin/nucleoplasmin family of nuclear chaperonesNPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingAnaplastic lymphoma kinase: signalling in development and diseaseNucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicityActivation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independentShuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformationTPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumorsDiversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activityWrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulatorsStructural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma KinaseActivation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathwayIdentification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophinPleiotropic signal transduction mediated by human CD30: a member of the tumor necrosis factor receptor (TNFR) familyIdentification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumorExpression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell linesActivation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell linesALK rearrangement in sickle cell trait-associated renal medullary carcinomaIdentification of a recurrent STRN/ALK fusion in thyroid carcinomasIdentification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA)Involvement of Grb2 adaptor protein in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated signaling and anaplastic large cell lymphoma growthNPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma.Primary cerebral ALK-1-positive anaplastic large cell lymphoma in a child. Case report and literature review.Proteomic analysis of anaplastic lymphoma cell lines: identification of potential tumour markers.Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy.Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer.Intrinsic structural disorder confers cellular viability on oncogenic fusion proteinsAberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilizationAnaplastic large cell lymphoma: a clinicopathologic analysis.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesThe tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions.The ALK inhibitor ASP3026 eradicates NPM-ALK⁺ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model.Alk+ CD30+ lymphomas: a distinct molecular genetic subtype of non-Hodgkin's lymphoma.The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.Anaplastic large cell lymphoma: pathological, molecular and clinical features.Translocations involving anaplastic lymphoma kinase (ALK).Translocations of the RARalpha gene in acute promyelocytic leukemia.Fusion of the SEC31L1 and ALK genes in an inflammatory myofibroblastic tumor.Nucleolar adaptation in human cancerAnaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.
P2860
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P2860
Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@ast
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@en
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@en-gb
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@nl
type
label
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@ast
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@en
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@en-gb
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@nl
prefLabel
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@ast
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@en
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@en-gb
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@nl
P2093
P2860
P921
P3181
P356
P1476
Role of the nucleophosmin (NPM ...... fusion protein in oncogenesis
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.17.4.2312
P407
P577
1997-04-01T00:00:00Z