Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis
about
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnoverMechanisms of gene regulation by fatty acidsGRAF1a is a brain-specific protein that promotes lipid droplet clustering and growth, and is enriched at lipid droplet junctionsA Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage has impaired glucose tolerance independent of body weight.Hepatocyte-Specific Depletion of UBXD8 Induces Periportal Steatosis in Mice Fed a High-Fat DietDerlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid dropletsUnsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin.The Niemann-Pick C1 gene is downregulated in livers of C57BL/6J mice by dietary fatty acids, but not dietary cholesterol, through feedback inhibition of the SREBP pathway.The p97-UBXD8 complex destabilizes mRNA by promoting release of ubiquitinated HuR from mRNPProtein segregase meddles in remodeling of mRNA-protein complexesThe intrinsically disordered membrane protein selenoprotein S is a reductase in vitro.UAS domain of Ubxd8 and FAF1 polymerizes upon interaction with long-chain unsaturated fatty acidsPeroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomainsDefining the role of DAG, mitochondrial function, and lipid deposition in palmitate-induced proinflammatory signaling and its counter-modulation by palmitoleateSubunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress.Fatty acid-regulated transcription factors in the liver.TRIENNIAL LACTATION SYMPOSIUM: Nutrigenomics in dairy cows: Nutrients, transcription factors, and techniques.Establishing the lipid droplet proteome: Mechanisms of lipid droplet protein targeting and degradation.Perturbations to the ubiquitin conjugate proteome in yeast δubx mutants identify Ubx2 as a regulator of membrane lipid composition.Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytesThe AAA+ ATPase p97, a cellular multitool.Ectopic Expression of WRINKLED1 Affects Fatty Acid Homeostasis in Brachypodium distachyon Vegetative Tissues.Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.The peroxisome biogenesis factors posttranslationally target reticulon homology domain-containing proteins to the endoplasmic reticulum membrane.The Role of Lipid Metabolism in T Lymphocyte Differentiation and Survival.Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids.Hepatocyte-specific depletion of ubiquitin regulatory X domain containing protein 8 accelerates fibrosis in a mouse non-alcoholic steatohepatitis model.UBXN3B positively regulates STING-mediated antiviral immune responses.
P2860
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P2860
Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@ast
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@en
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@nl
type
label
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@ast
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@en
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@nl
prefLabel
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@ast
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@en
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@nl
P2093
P2860
P356
P1476
Identification of Ubxd8 protei ...... ator of triglyceride synthesis
@en
P2093
Hongbing Yao
Hyeonwoo Kim
Joon No Lee
Kayson Weng
P2860
P304
21424-21429
P356
10.1073/PNAS.1011859107
P407
P577
2010-11-29T00:00:00Z