Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.

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http://www.wikidata.org/entity/Q34417983

Q34417983

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Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia.Methyl salicylate lactoside inhibits inflammatory response of fibroblast-like synoviocytes and joint destruction in collagen-induced arthritis in mice Pinocembrin protects human brain microvascular endothelial cells against fibrillar amyloid-β(1-40) injury by suppressing the MAPK/NF-κB inflammatory pathways Radix Achyranthis Bidentatae improves learning and memory capabilities in ovariectomized rats.A specific RAGE-binding peptide biopanning from phage display random peptide library that ameliorates symptoms in amyloid β peptide-mediated neuronal disorder.Quercetin protects human brain microvascular endothelial cells from fibrillar β-amyloid1-40-induced toxicity DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway.RAGE regulation and signaling in inflammation and beyond.Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.Flavonoids in modulation of cell survival signalling pathways.Investigation of phosphoproteome in RAGE signaling.Prevention of protein glycation by natural compounds.Pinocembrin Attenuates Mitochondrial Dysfunction in Human Neuroblastoma SH-SY5Y Cells Exposed to Methylglyoxal: Role for the Erk1/2-Nrf2 Signaling Pathway.Biological Properties and Therapeutic Applications of Propolis.Pinocembrin attenuates 6-OHDA-induced neuronal cell death through Nrf2/ARE pathway in SH-SY5Y cells.Pinocembrin protects SH-SY5Y cells against MPP+-induced neurotoxicity through the mitochondrial apoptotic pathway.Can Co-Activation of Nrf2 and Neurotrophic Signaling Pathway Slow Alzheimer's Disease?Mechanistic comparison of current pharmacological treatments and novel phytochemicals to target amyloid peptides in Alzheimer's and neurodegenerative diseases.Chemical composition and disruption of quorum sensing signaling in geographically diverse United States propolis.Pinocembrin suppresses TGF-β1-induced epithelial-mesenchymal transition and metastasis of human Y-79 retinoblastoma cells through inactivating αvβ3 integrin/FAK/p38α signaling pathway.Scutellaria baicalensis stem-leaf total flavonoid reduces neuronal apoptosis induced by amyloid beta-peptide (25-35).Pinocembrin Suppresses H2O2-Induced Mitochondrial Dysfunction by a Mechanism Dependent on the Nrf2/HO-1 Axis in SH-SY5Y Cells.l-3-n-Butylphthalide attenuates β-amyloid-induced toxicity in neuroblastoma SH-SY5Y cells through regulating mitochondrion-mediated apoptosis and MAPK signaling.Protection of mice against lipopolysaccharide-induced endotoxic shock by pinocembrin is correlated with regulation of cytokine secretion.Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease.New propolis type from north-east Brazil: chemical composition, antioxidant activity and botanical origin.p38 MAPK-MK2 pathway regulates the heat-stress-induced accumulation of reactive oxygen species that mediates apoptotic cell death in glial cells.Hydroalcoholic extract of red propolis promotes functional recovery and axon repair after sciatic nerve injury in rats.Methyl Salicylate Lactoside Protects Neurons Ameliorating Cognitive Disorder Through Inhibiting Amyloid Beta-Induced Neuroinflammatory Response in Alzheimer's Disease.Validation of RetroPath, a computer-aided design tool for metabolic pathway engineering.No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases.Inhibitory effect of propolis on the development of AA amyloidosis.The role of neutrophil granule proteins in neuroinflammation and Alzheimer's disease

P2860

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P2860

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.

Item

http://www.wikidata.org/entity/Q34417983

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Pinocembrin protects against β ...... ochondrion-mediated apoptosis.

@ast

Pinocembrin protects against β ...... ochondrion-mediated apoptosis.

@en

Pinocembrin protects against β ...... dvanced glycation end products

@nl

type

Item

label

Pinocembrin protects against β ...... ochondrion-mediated apoptosis.

@ast

Pinocembrin protects against β ...... ochondrion-mediated apoptosis.

@en

Pinocembrin protects against β ...... dvanced glycation end products

@nl

prefLabel

Pinocembrin protects against β ...... ochondrion-mediated apoptosis.

@ast

Pinocembrin protects against β ...... ochondrion-mediated apoptosis.

@en

Pinocembrin protects against β ...... dvanced glycation end products

@nl

P1476

Pinocembrin protects against β ...... ochondrion-mediated apoptosis.

@en

P2093

Cai-Xia Wu

http://www.w3.org/2001/XMLSchema#string

Dan Zhou

http://www.w3.org/2001/XMLSchema#string

Fan Yang

http://www.w3.org/2001/XMLSchema#string

Guan-Hua Du

http://www.w3.org/2001/XMLSchema#string

Li Zhang

http://www.w3.org/2001/XMLSchema#string

Rui Liu

http://www.w3.org/2001/XMLSchema#string

Shuo Tian

http://www.w3.org/2001/XMLSchema#string

Tian-Tai Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase.

Mammalian MAP kinase signalling cascades

JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine

Alzheimer's disease is a synaptic failure

Intracellular amyloid-beta in Alzheimer's disease

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

Developments of a water-maze procedure for studying spatial learning in the rat

P2888

1741-7015-10-105

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105

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scholarly article

P356

10.1186/1741-7015-10-105

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English

P478

http://www.w3.org/2001/XMLSchema#string

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2012-09-18T00:00:00Z

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230878411

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1017434576

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22989295

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P921

mitochondrion

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3542580

http://www.w3.org/2001/XMLSchema#string

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.

about

P2860

P2860

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.

description

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type

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P1433

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P932

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P932