IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.
about
Ectopic lymphoid follicles: inducible centres for generating antigen-specific immune responses within tissuesInterleukin-27: balancing protective and pathological immunityInterleukin-27 in T cell immunityPotential of Cells and Cytokines/Chemokines to Regulate Tertiary Lymphoid Structures in Human DiseasesRegulators of Tfh Cell DifferentiationThe regulation of T follicular helper responses during infectionMycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12Gene expression profiling of the response to interferon beta in Epstein-Barr-transformed and primary B cells of patients with multiple sclerosisEctopic lymphoid neogenesis in rheumatic autoimmune diseases.IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination.Crucial roles of interleukin-7 in the development of T follicular helper cells and in the induction of humoral immunity.IL-12 family cytokines: immunological playmakersIL-27-induced modulation of autoimmunity and its therapeutic potential.Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization.CD4 T Cells Mediate Both Positive and Negative Regulation of the Immune Response to HIV Infection: Complex Role of T Follicular Helper Cells and Regulatory T Cells in PathogenesisThe transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa.The Yin and Yang aspects of IL-27 in induction of cancer-specific T-cell responses and immunotherapy.IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.Cell-Intrinsic gp130 Signaling on CD4+ T Cells Shapes Long-Lasting Antiviral ImmunityIncreased Frequency of T Follicular Helper Cells and Elevated Interleukin-27 Plasma Levels in Patients with Pemphigus.Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages.Functional STAT3 deficiency compromises the generation of human T follicular helper cells.LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6Distinct germinal center selection at local sites shapes memory B cell response to viral escapeThe origins, function, and regulation of T follicular helper cellsB and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1JAK and STAT signaling molecules in immunoregulation and immune-mediated disease.Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection.Preparation, characterization, and determination of immunological activities of transfer factor specific to human sperm antigen.T follicular helper cell diversity and plasticityBlockade of STAT3 in T Cells Inhibits Germinal Center Reactions against Intranasal Allergens.The Emerging Role of Interleukin-21 in Transplantation.The role of IL-27 in the induction of anti-tumor cytotoxic T lymphocyte responseThe transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.Modulation of inflammation by interleukin-27.Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection.Enforced Expression of CXCR5 Drives T Follicular Regulatory-Like Features in Foxp3+ T Cells.Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells
P2860
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P2860
IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
IL-27 supports germinal center ...... of T follicular helper cells.
@ast
IL-27 supports germinal center ...... of T follicular helper cells.
@en
IL-27 supports germinal center ...... of T follicular helper cells.
@nl
type
label
IL-27 supports germinal center ...... of T follicular helper cells.
@ast
IL-27 supports germinal center ...... of T follicular helper cells.
@en
IL-27 supports germinal center ...... of T follicular helper cells.
@nl
prefLabel
IL-27 supports germinal center ...... of T follicular helper cells.
@ast
IL-27 supports germinal center ...... of T follicular helper cells.
@en
IL-27 supports germinal center ...... of T follicular helper cells.
@nl
P2093
P2860
P50
P356
P1476
IL-27 supports germinal center ...... n of T follicular helper cells
@en
P2093
David A Fulcher
Dimitry M Danilenko
Frederic J de Sauvage
Hart S Dengler
Jennifer H Cox
Marcel Batten
Matthew C Cook
Melanie Wong
Nandhini Ramamoorthi
Noelyn M Kljavin
P2860
P304
P356
10.1084/JEM.20100064
P407
P577
2010-11-22T00:00:00Z