Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
about
A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphomaBinding studies of a large antiviral polyamide to a natural HPV sequence.Understanding mixed sequence DNA recognition by novel designed compounds: the kinetic and thermodynamic behavior of azabenzimidazole diamidinesDesign of sequence-specific DNA binding molecules for DNA methyltransferase inhibition.Unravelling the genomic targets of small molecules using high-throughput sequencing.Advancing small-molecule-based chemical biology with next-generation sequencing technologies.Identification of Sequence Specificity of 5-Methylcytosine Oxidation by Tet1 Protein with High-Throughput Sequencing.Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair.Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer GenomeThreading polyintercalators with extremely slow dissociation rates and extended DNA binding sitesSynthetic genome readers target clustered binding sites across diverse chromatin states.Imidazolyl-Naphthalenediimide-Based Threading Intercalators of DNA.Comparative Analysis of DNA-Binding Selectivity of Hairpin and Cyclic Pyrrole-Imidazole Polyamides Based on Next-Generation Sequencing.Interactions of two large antiviral polyamides with the long control region of HPV16.Sequence-Selective Formation of Synthetic H-Bonded Duplexes.Modulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.H-Bond Self-Assembly: Folding versus Duplex Formation.Deciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing.Tandem trimer pyrrole-imidazole polyamide probes targeting 18 base pairs in human telomere sequences.β-Alanine and N-terminal cationic substituents affect polyamide-DNA binding.A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA.Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates.H-Bonded Duplexes based on a Phenylacetylene Backbone
P2860
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P2860
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@ast
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@en
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@nl
type
label
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@ast
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@en
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@nl
prefLabel
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@ast
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@en
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@nl
P2860
P50
P356
P1476
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
@en
P2093
Abigail S Yu
P2860
P304
17814-17822
P356
10.1021/JA308888C
P407
P577
2012-10-10T00:00:00Z