Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors.
about
Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner earDrug-dependent behaviors and nicotinic acetylcholine receptor expressions in Caenorhabditis elegans following chronic nicotine exposure.Novel and conserved protein macoilin is required for diverse neuronal functions in Caenorhabditis elegansHaemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantelMouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the alpha7 acetylcholine receptor through a cytoplasmic coiled-coil domainNicotinic acetylcholine receptor alpha7 subunits with a C2 cytoplasmic loop yellow fluorescent protein insertion form functional receptors.The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits.Protein interactions involving the gamma2 large cytoplasmic loop of GABA(A) receptors modulate conductance.RIC-3 exclusively enhances the surface expression of human homomeric 5-hydroxytryptamine type 3A (5-HT3A) receptors despite direct interactions with 5-HT3A, -C, -D, and -E subunitsRic-3 promotes alpha7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites.The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7.The use of Xenopus oocytes in drug screening.Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.Cell-specific effects on surface α7 nicotinic receptor expression revealed by over-expression and knockdown of rat RIC3 protein.Differential subcellular localization of RIC-3 isoforms and their role in determining 5-HT3 receptor composition.RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulationStructural answers and persistent questions about how nicotinic receptors work.Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes.Ly6h regulates trafficking of alpha7 nicotinic acetylcholine receptors and nicotine-induced potentiation of glutamatergic signaling.Engineering a prokaryotic Cys-loop receptor with a third functional domain.Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human α7-Nicotinic Acetylcholine Receptor Interactome.Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loopMuscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity.RIC-3: a nicotinic acetylcholine receptor chaperoneAn overview of trafficking and assembly of neurotransmitter receptors and ion channels (Review).Mutations of cytosolic loop residues impair assembly and maturation of alpha7 nicotinic acetylcholine receptors.Postsynaptic scaffolds for nicotinic receptors on neurons.Cellular trafficking of nicotinic acetylcholine receptors.Understanding the Bases of Function and Modulation of α7 Nicotinic Receptors: Implications for Drug Discovery.Direct interaction of the resistance to inhibitors of cholinesterase type 3 protein with the serotonin receptor type 3A intracellular domain.Ric-3 chaperone-mediated stable cell-surface expression of the neuronal alpha7 nicotinic acetylcholine receptor in mammalian cells.Proteins and chemical chaperones involved in neuronal nicotinic receptor expression and function: an update.Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras.Molecular dissection of Cl--selective Cys-loop receptor points to components that are dispensable or essential for channel activity.Host-cell specific effects of the nicotinic acetylcholine receptor chaperone RIC-3 revealed by a comparison of human and Drosophila RIC-3 homologues.Molecular characterization and localization of the RIC-3 protein, an effector of nicotinic acetylcholine receptor expression.Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors.An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors.The conserved RIC-3 coiled-coil domain mediates receptor-specific interactions with nicotinic acetylcholine receptors.Functional characterization of Musca glutamate- and GABA-gated chloride channels expressed independently and coexpressed in Xenopus oocytes.
P2860
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P2860
Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors.
description
2005 nî lūn-bûn
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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
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2005年學術文章
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name
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@ast
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@en
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@nl
type
label
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@ast
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@en
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@nl
prefLabel
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@ast
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@en
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@nl
P2093
P2860
P50
P356
P1476
Dual role of the RIC-3 protein ...... tinic acetylcholine receptors.
@en
P2093
José A Ortiz
José Mulet
Manuel Criado
Mar Castillo
Salvador Sala
Susana Gerber
P2860
P304
27062-27068
P356
10.1074/JBC.M503746200
P407
P577
2005-05-31T00:00:00Z