A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes.
about
The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overloadDisruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathyMyopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assembliesA new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-κB pathway in skeletal muscleANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy geneMultiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscleANKRD1 acts as a transcriptional repressor of MMP13 via the AP-1 siteMutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathyCardiotoxicity in childhood cancer survivors: strategies for prevention and managementScaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and DiseaseCARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complexProteasome-mediated degradation of the coactivator p300 impairs cardiac transcriptionBrn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglionStructural and regulatory roles of muscle ankyrin repeat protein family in skeletal muscleInvolvement of GADD153 and cardiac ankyrin repeat protein in hypoxia-induced apoptosis of H9c2 cellsInvolvement of GADD153 and cardiac ankyrin repeat protein in cardiac ischemia-reperfusion injuryIdentification of candidate transcriptional modulators involved in successful regeneration after nerve injuryMulti-tasking role of the mechanosensing protein Ankrd2 in the signaling network of striated muscle.Mechanisms of anthracycline cardiotoxicity and strategies to decrease cardiac damage.Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity.A mouse model for juvenile doxorubicin-induced cardiac dysfunctionMolecular remodeling of left and right ventricular myocardium in chronic anthracycline cardiotoxicity and post-treatment follow up.Cardiomyocyte death in doxorubicin-induced cardiotoxicityThree-dimensional culture alters primary cardiac cell phenotype.Cytosolic CARP promotes angiotensin II- or pressure overload-induced cardiomyocyte hypertrophy through calcineurin accumulationMechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection?Carp, a cardiac ankyrin-repeated protein, and its new homologue, Arpp, are differentially expressed in heart, skeletal muscle, and rhabdomyosarcomas26S proteasome regulation of Ankrd1/CARP in adult rat ventricular myocytes and human microvascular endothelial cellsCardiac ankyrin repeat protein attenuates cardiac hypertrophy by inhibition of ERK1/2 and TGF-β signaling pathways.Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue.CARP, a cardiac ankyrin repeat protein, is up-regulated during wound healing and induces angiogenesis in experimental granulation tissue.Expression of Ankrd2 in fast and slow muscles and its response to stretch are consistent with a role in slow muscle function.Probing muscle ankyrin-repeat protein (MARP) structure and functionProfiling of skeletal muscle Ankrd2 protein in human cardiac tissue and neonatal rat cardiomyocytes.Targeted inhibition of ANKRD1 disrupts sarcomeric ERK-GATA4 signal transduction and abrogates phenylephrine-induced cardiomyocyte hypertrophy.Protecting against anthracycline-induced myocardial damage: a review of the most promising strategies.Mutations in the Z-band protein myopalladin gene and idiopathic dilated cardiomyopathy.Transcriptional deregulation and a missense mutation define ANKRD1 as a candidate gene for total anomalous pulmonary venous return.Muscle giants: molecular scaffolds in sarcomerogenesis.Upregulated expression of cardiac ankyrin repeat protein in human failing hearts due to arrhythmogenic right ventricular cardiomyopathy.
P2860
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P2860
A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes.
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@ast
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@en
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@nl
type
label
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@ast
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@en
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@nl
prefLabel
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@ast
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@en
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@nl
P2093
P2860
P356
P1476
A novel cardiac-restricted tar ...... itor cells and cardiomyocytes.
@en
P2093
Abdishoo S
Isterabadi LB
Jeyaseelan R
P2860
P304
22800-22808
P356
10.1074/JBC.272.36.22800
P407
P577
1997-09-01T00:00:00Z