Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.
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Development of bisphosphonates.Interventions for treating osteonecrosis of the jaw bones associated with bisphosphonatesDrugs in development: bisphosphonates and metalloproteinase inhibitorsInnovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis PathwayProdrugs of phosphonates and phosphates: crossing the membrane barrierBisphosphonates: from bench to bedsideBisphosphonates induce apoptosis in human breast cancer cell linesThe bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxelSynergistic action of statins and nitrogen-containing bisphosphonates in the development of rhabdomyolysis in L6 rat skeletal myoblastsMicroglial cells in astroglial cultures: a cautionary note.Colon Macrophages Polarized by Commensal Bacteria Cause Colitis and Cancer through the Bystander Effect.F4/80+ Host Macrophages Are a Barrier to Murine Embryonic Stem Cell-Derived Hematopoietic Progenitor Engraftment In Vivo.Anti-tumour activity of bisphosphonates in human myeloma cells.Osseointegration of dental implants in patients undergoing bisphosphonate treatment: a literature review.The pharmacology of bisphosphonates and new insights into their mechanisms of action.Clodronate exerts an anabolic effect on articular chondrocytes mediated through the purinergic receptor pathway.Bisphosphonates in the adjuvant treatment of cancer: experimental evidence and first clinical results. International Bone and Cancer Study Group (IBCG).Bisphosphonates and the prevention of metastasis: first evidences from preclinical and clinical studies.Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy.Effects of ibandronate-hydroxyapatite on resorptive activity of osteoclasts.Site specific effects of zoledronic acid during tibial and mandibular fracture repair.Bisphosphonate associated osteonecrosis of the jaw: an update on pathophysiology, risk factors, and treatmentClodronate-containing liposomes attenuate lung injury in rats with severe acute pancreatitis.Bisphosphonates and periodontics: potential applications for regulation of bone mass in the periodontium and other therapeutic/diagnostic uses.Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro.Bisphosphonates' antiangiogenic potency in the development of bisphosphonate-associated osteonecrosis of the jaws: influence on microvessel sprouting in an in vivo 3D Matrigel assay.Bisphosphonates pathway.Clodronate: mechanisms of action on bone remodelling and clinical use in osteometabolic disorders.Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells.The potential role of bisphosphonates in prostate cancer.Are gastric mucosal macrophages responsible for gastric injury in acute pancreatitis?Novel therapy to reverse the cellular effects of bisphosphonates on primary human oral fibroblastsBisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cellsLigand-modified aminobisphosphonate for linking proteins to hydroxyapatite and bone surface.Advances in the use of bisphosphonates in the prostate cancer setting.Bisphosphonates significantly increase the activity of doxorubicin or vincristine against canine malignant histiocytosis cells.Pharmacological management of metastatic boney pain.A Novel Loading Method for Doxycycline Liposomes for Intracellular Drug Delivery: Characterization of In Vitro and In Vivo Release Kinetics and Efficacy in a J774A.1 Cell Line Model of Mycobacterium smegmatis InfectionModulating P2X7 Receptor Signaling during Rheumatoid Arthritis: New Therapeutic Approaches for BisphosphonatesClodronate in the prevention and treatment of skeletal metastasis.
P2860
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P2860
Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@ast
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@en
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@nl
type
label
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@ast
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@en
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@nl
prefLabel
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@ast
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@en
Clodronate and liposome-encaps ...... , by mammalian cells in vitro.
@nl
P2093
P1476
Clodronate and liposome-encaps ...... e, by mammalian cells in vitro
@en
P2093
Blackburn GM
Mönkkönen J
P2860
P304
P356
10.1359/JBMR.1997.12.9.1358
P577
1997-09-01T00:00:00Z