Mycobacterium ulcerans toxic macrolide, mycolactone modulates the host immune response and cellular location of M. ulcerans in vitro and in vivo.
about
Mycolactone diffuses from Mycobacterium ulcerans-infected tissues and targets mononuclear cells in peripheral blood and lymphoid organsGlobally distributed mycobacterial fish pathogens produce a novel plasmid-encoded toxic macrolide, mycolactone FBacterial Toxins as Pathogen Weapons Against PhagocytesMycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer LesionsEvolution of polyketide synthases in bacteriaDevelopment of highly organized lymphoid structures in Buruli ulcer lesions after treatment with rifampicin and streptomycinDetection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human TissueSecondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicinThe pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ERAntioxidants protect keratinocytes against M. ulcerans mycolactone cytotoxicityEvaluating decontamination protocols for the isolation of Mycobacterium ulcerans from swabsImpact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis.Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans diseaseBCG-mediated protection against Mycobacterium ulcerans infection in the mouse.Secondary Buruli ulcer skin lesions emerging several months after completion of chemotherapy: paradoxical reaction or evidence for immune protection?Proteomic analysis of the action of the Mycobacterium ulcerans toxin mycolactone: targeting host cells cytoskeleton and collagen.Buruli ulcer.Survey of water bugs in bankim, a new buruli ulcer endemic area in cameroon.Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression.Microbiological, histological, immunological, and toxin response to antibiotic treatment in the mouse model of Mycobacterium ulcerans diseaseStructure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans.Mycobacterium ulcerans fails to infect through skin abrasions in a guinea pig infection model: implications for transmission.Evidence for an intramacrophage growth phase of Mycobacterium ulcerans.Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model.Recombinant BCG Expressing Mycobacterium ulcerans Ag85A Imparts Enhanced Protection against Experimental Buruli ulcer.Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis.Interferon-γ Is a Crucial Activator of Early Host Immune Defense against Mycobacterium ulcerans Infection in Mice.Challenges Associated with Management of Buruli Ulcer/Human Immunodeficiency Virus Coinfection in a Treatment Center in Ghana: A Case Series Study.Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has implications for the control of infectionLocal Cellular Immune Responses and Pathogenesis of Buruli Ulcer Lesions in the Experimental Mycobacterium Ulcerans Pig Infection Model.Mycobacterium ulcerans causes minimal pathogenesis and colonization in medaka (Oryzias latipes): an experimental fish model of disease transmissionMycolactone is responsible for the painlessness of Mycobacterium ulcerans infection (buruli ulcer) in a murine studyMycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria.Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans.When two is better than one: macrophages and neutrophils work in concert in innate immunity as complementary and cooperative partners of a myeloid phagocyte system.History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease).Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer.Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease.Mycobacterium ulcerans mycolactone interferes with adhesion, migration and proliferation of primary human keratinocytes and HaCaT cell line.Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin.
P2860
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P2860
Mycobacterium ulcerans toxic macrolide, mycolactone modulates the host immune response and cellular location of M. ulcerans in vitro and in vivo.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@ast
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@en
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@nl
type
label
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@ast
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@en
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@nl
prefLabel
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@ast
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@en
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo.
@nl
P2093
P1476
Mycobacterium ulcerans toxic m ...... ulcerans in vitro and in vivo
@en
P2093
Armand Mve-Obiang
John Hayman
Pamela Long Claus Small
Sarojini Adusumilli
Wayne Meyers
P2860
P304
P356
10.1111/J.1462-5822.2005.00557.X
P577
2005-09-01T00:00:00Z