Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1. - Wikidata - awgldk - TriplyDB

Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1.

Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1.

http://www.wikidata.org/entity/Q34444604

about

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1 Identification of a MAD2-binding protein, CMT2, and its role in mitosis.Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1 Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes.Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1 Cdc20 associates with the kinase aurora2/Aik Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells Mad2 transiently associates with an APC/p55Cdc complex during mitosis Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry.Crystal Structure of the N-terminal Domain of the Yeast General Corepressor Tup1p and Its Functional Implications Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase Mitotic regulation of the APC activator proteins CDC20 and CDH1 Identification of genes periodically expressed in the human cell cycle and their expression in tumors The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae.Inhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit.Reconstructing dynamic gene regulatory networks from sample-based transcriptional data Cdc20 and securin overexpression predict short-term breast cancer survival.A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae.Changes in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation.Targeting Cell Cycle Proteins in Breast Cancer Cells with siRNA by Using Lipid-Substituted Polyethylenimines.Human T-lymphotropic virus type 1 oncoprotein tax promotes unscheduled degradation of Pds1p/securin and Clb2p/cyclin B1 and causes chromosomal instability.Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC)The anaphase-promoting complex: a key factor in the regulation of cell cycle.Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells.Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1).Transcriptional signatures of somatic neoblasts and germline cells in Macrostomum lignano.Transcriptional response to circumscribed cortical brain ischemia: spatiotemporal patterns in ischemic vs. remote non-ischemic cortex.Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway.Elovl1 and p55Cdc genes are localized in a tail-to-tail array and are co-expressed in proliferating cells.Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.

P2860

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P2860

Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1.

http://www.wikidata.org/entity/Q34444604

description

1997 nî lūn-bûn

@nan

1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

@ja

1997年学术文章

@wuu

1997年学术文章

@zh-cn

1997年学术文章

@zh-hans

1997年学术文章

@zh-my

1997年学术文章

@zh-sg

1997年學術文章

@yue

name

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@ast

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@en

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@nl

type

label

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@ast

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@en

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@nl

prefLabel

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@ast

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@en

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@nl

P1433

Q34444604-B78150A2-2D69-4FC4-B8DF-C1DFEE881126

P1476

Q34444604-1BABCA81-1385-4A9F-9580-0591C68E9855

P2093

Q34444604-2F64BD6C-1588-40C1-BF48-C26B5B184F8C

P2860

Q34444604-0716A5C3-2B51-466B-B3F1-2C5240EA4724

Q34444604-07AB9341-9D16-4D50-AC0B-16D807A61BF7

Q34444604-0850AE50-A493-4D51-AD65-BEE6DF248F79

Q34444604-0B60408F-C549-41F1-863E-25ABE4ACD5B3

Q34444604-0DC75165-F859-4FDF-A5B8-CAAB8DCB74EC

Q34444604-0F9C92A8-B460-482C-8945-2E8365C9D3AF

Q34444604-14007D6B-753F-466A-801E-95DB570D6A0A

Q34444604-17697F9A-50B5-446E-8B4A-89025E69B995

Q34444604-194935E1-4558-4416-8D22-FD3BF3430E23

Q34444604-1D683383-C59E-4BD2-B898-91F8256052A4

P304

Q34444604-9E6FBAB4-86F1-4240-A124-2EA863D0969D

P31

Q34444604-2278F909-CF60-4521-BB9C-8AD5EE139DCD

P356

Q34444604-680A787E-4D3C-47B3-8113-C4CE1C1067DD

P407

Q34444604-071BC71D-63A1-45C7-BEF9-9A860B2C3D03

P433

Q34444604-C03C7FA0-CBE3-48F2-88F4-95D81DC0CE67

P478

Q34444604-05E8995C-C58A-4CDF-8179-9FB50E18C816

P577

Q34444604-CAAA5580-89DC-42F4-9F55-0A19002864C8

P5875

Q34444604-6A09FD8F-8766-4B98-B25E-850AD26483C0

P698

Q34444604-4151B046-49F3-41C2-9A3B-5833E1F13650

P921

Q34444604-7219FA99-28EC-480D-A22B-9D2FE28F1B95

P356

JBC.272.45.28501

P1433

Journal of Biological Chemistry

P1476

Cell cycle-regulated expressio ...... n homolog of CDC20/Fizzy/slp1.

@en

P2093

Weinstein J

http://www.w3.org/2001/XMLSchema#string

P2860

A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

Delay of HeLa cell cleavage into interphase using dihydrocytochalasin B: retention of a postmitotic spindle and telophase disc correlates with synchronous cleavage recovery

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Cyclin is degraded by the ubiquitin pathway

P304

28501-28511

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.272.45.28501

http://www.w3.org/2001/XMLSchema#string

P407

P433

45

http://www.w3.org/2001/XMLSchema#string

P478

272

http://www.w3.org/2001/XMLSchema#string

P577

1997-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13876820

http://www.w3.org/2001/XMLSchema#string

P698

9353311

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation