Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay.
about
Epigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based ModelsState-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiologyInhibition of microglia activation as a phenotypic assay in early drug discoveryA perspective on stem cell modeling of amyotrophic lateral sclerosisImpact of lifetime opioid exposure on arterial stiffness and vascular age: cross-sectional and longitudinal studies in men and women.Investigating human disease using stem cell models.Chemical approaches to studying stem cell biology.Advances in reprogramming-based study of neurologic disordersiPSC technology--Powerful hand for disease modeling and therapeutic screenTopoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.Neural stem cells as tools for drug discovery: novel platforms and approaches.Phenotypic screens targeting neurodegenerative diseases.Neural stem and progenitor cells in health and disease.Toward stem cell-based phenotypic screens for neurodegenerative diseases.Induced pluripotent stem cell technology for modelling and therapy of cerebellar ataxia.Enantioselective Organocatalytic Synthesis of a Secoyohimbane-Inspired Compound Collection with Neuritogenic Activity.Glial cells as drug targets: What does it take?Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.Induced pluripotent stem cell technology: a decade of progress.Human induced pluripotent stem cells for modelling neurodevelopmental disorders.A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease.Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype.[Possible applications of new stem cell sources in neurology].Derivation of Human Induced Pluripotent Stem Cell (iPSC) Lines and Mechanism of Pluripotency: Historical Perspective and Recent Advances.Neonatal mouse cortical but not isogenic human astrocyte feeder layers enhance the functional maturation of induced pluripotent stem cell-derived neurons in culture.[Induced pluripotent stem cells. A new resource in modern medicine].Genetic validation of a therapeutic target in a mouse model of ALS.
P2860
Q26772307-07FB557E-768A-4F48-BE33-15A81FA138CFQ26852097-52D005CD-BCAC-40BA-A179-27F595BF08D5Q26996061-62F34AF6-C6F1-4A60-B642-63DCAAEE6522Q28080614-4E42D874-2363-47FF-8AC3-74895DA40961Q33744915-DE2E5BA2-6F50-4B7D-95EC-40BDA16C61B7Q34431170-3A3F96B0-84C9-453A-BB2B-A5BEA01569A7Q34522598-E3D708DB-BDD1-46EC-A686-3DE79377CAB0Q35635245-A427B57F-4041-4341-8914-C1CA84F37074Q36082427-B2C22E72-0F50-491C-BE1A-14B563BA6066Q37540505-35611374-7A90-4F67-A4A1-BF3C2422A9C5Q38110960-E682B4DC-4C5A-40F4-806B-CE320AC4903BQ38130052-64C600EA-D798-45AA-88D0-40DA95BC4247Q38143704-9F957DA6-28DF-41CD-B471-9E3BC3940006Q38489289-73CB7699-CA4E-4680-B392-E86054D0CC2EQ38542017-7CD3E1AE-78F2-40B8-A2DE-717710F1AEB6Q38706972-2A5DCB98-337A-4B68-A34D-858BA78E085AQ38819291-953101AA-30A8-426A-95E1-461B83C8DB22Q38853070-D09B4EE1-EC61-4106-AAF7-4EB88AFDD82AQ39040578-040EAA22-06C7-4201-B54E-F0EC5F63A32BQ39247913-2417321E-60D5-4BA5-B52C-D32C4C12F2FDQ39432513-3958B07E-6DEC-4E4E-A044-2574464F7CBEQ39451018-FC6C05ED-17B7-44A9-B2EE-99488565E62FQ40195531-176CEAFC-04DB-414E-ADB4-0CBDC3665D71Q45240828-B66AA2D4-DEDB-47A3-87E4-81A0D8A9482DQ47296243-FBB21891-D660-4B5E-B0A1-70D001A081A7Q47325614-B393DD73-3BE8-4001-8CE7-AD6D40AF1546Q48887430-E9521B1D-C8C0-48B3-B78D-85916C414D8BQ51064372-E6DB5926-2F14-4C0C-A52B-79A311582656
P2860
Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@ast
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@en
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@nl
type
label
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@ast
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@en
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@nl
prefLabel
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@ast
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@en
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@nl
P2093
P50
P921
P1433
P1476
Discovery of inhibitors of mic ...... m-cell-based phenotypic assay.
@en
P2093
Alexander Böcker
Christiane Peiker
Jens C Schwamborn
Juan A Parga
Mark Slack
Martin Stehling
Michael Glatza
Peter Reinhardt
Susanne Höing
P304
P356
10.1016/J.STEM.2012.07.005
P407
P577
2012-10-11T00:00:00Z