Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.
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Th17 Cells in Type 1 Diabetes: Role in the Pathogenesis and Regulation by Gut MicrobiomeP2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway.Current status of immunomodulatory and cellular therapies in preclinical and clinical islet transplantation.Combination therapy with an anti-IL-1β antibody and GAD65 DNA vaccine can reverse recent-onset diabetes in the RIP-GP mouse model.Potential role of IL-17-producing iNKT cells in type 1 diabetes.Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation.Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes.Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders.CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L.CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes.Immune protective effect of human alpha-1-antitrypsin gene during β cell transplantation in diabetic mice.Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+ T-cell effector differentiation by IL-2 modulation.Innate immunity and resistance to tolerogenesis in allotransplantationDouble deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice.CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms.
P2860
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P2860
Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@ast
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@en
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@nl
type
label
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@ast
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@en
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@nl
prefLabel
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@ast
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@en
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@nl
P2093
P2860
P50
P356
P1433
P1476
Interleukin-1β produced in res ...... g of tolerizing immunotherapy.
@en
P2093
Dimeng Pang
Emily Duggan
Helen Thomas
Leonard C Harrison
Sebastien Bertin-Maghit
Shannon Best
Thomas W H Kay
P2860
P304
P356
10.2337/DB10-0104
P407
P577
2010-10-27T00:00:00Z