The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway.
about
Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeletonNeurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2Integrated proteomics identified novel activation of dynein IC2-GR-COX-1 signaling in neurofibromatosis type I (NF1) disease model cellsMultiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.NF1 inactivation in adult acute myelogenous leukemiaExpression and significance of Rac1, Pak1 and Rock1 in gastric carcinoma.The NF1 gene revisited - from bench to bedside.Nf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathwaysThe CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cellsMicroRNAome profiling in benign and malignant neurofibromatosis type 1-associated nerve sheath tumors: evidences of PTEN pathway alterations in early NF1 tumorigenesisNovel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft modelHigh prevalence of hyposalivation in individuals with neurofibromatosis 1: a case-control study.Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patientALTERED CALCIUM CURRENTS AND AXONAL GROWTH IN Nf1 HAPLOINSUFFICIENT MICESchweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.Partial Blindness to Submicron Topography in NF1 Haploinsufficient Cultured Fibroblasts Indicates a New Function of Neurofibromin in Regulation of Mechanosensoric.Targeted overexpression of TGF-α in the corneal epithelium of adult transgenic mice induces changes in anterior segment morphology and activates noncanonical Wnt signaling.Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.Roles of LIM kinases in central nervous system function and dysfunction.Nuclear import mechanism of neurofibromin for localization on the spindle and function in chromosome congression.Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1.Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion.Neurofibromin physically interacts with the N-terminal domain of focal adhesion kinaseMicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells.Effect of Robo4 on retinal endothelial permeability.Neurofibromin Regulates Seizure Attacks in the Rat Pilocarpine-Induced Model of Epilepsy.
P2860
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P2860
The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@ast
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@en
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@nl
type
label
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@ast
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@en
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@nl
prefLabel
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@ast
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@en
The neurofibromatosis type 1 g ...... ho-ROCK-LIMK2-cofilin pathway.
@nl
P2093
P2860
P356
P1476
The neurofibromatosis type 1 g ...... Rho-ROCK-LIMK2-cofilin pathway
@en
P2093
Hideyuki Saya
Kiyotaka Fujii
Kunio Matsumoto
Liping Feng
Norie Araki
Shunji Yunoue
Siriporn Patrakitkomjorn
Tatsuya Ozawa
Toshihiro Hara
Yasuko Ichikawa
P2860
P304
39524-39533
P356
10.1074/JBC.M503707200
P407
P577
2005-09-16T00:00:00Z