Recent advances in non-competitive mGlu5 receptor antagonists and their potential therapeutic applications.
about
Advances in the treatment of fragile X syndromeAllosteric modulation of metabotropic glutamate receptors.mGluR5 has a critical role in inhibitory learning.The [F]2-Fluoro-1,3-thiazolyl Moiety - an Easily-Accessible Structural Motif for Prospective Molecular Imaging Radiotracers.Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP.Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEPQuantification of metabotropic glutamate subtype 5 receptors in the brain by an equilibrium method using 18F-SP203Design and synthesis of novel heterobiaryl amides as metabotropic glutamate receptor subtype 5 antagonistsComputational models of neuronal biophysics and the characterization of potential neuropharmacological targets.Are compounds acting at metabotropic glutamate receptors the answer to treating depression?mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo.Metabotropic glutamate receptor ligands as potential therapeutics for addictionAllosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.Metabotropic glutamate subtype 5 receptors are quantified in the human brain with a novel radioligand for PETAllosteric modulators for mGlu receptors.Metabotropic glutamate receptors: physiology, pharmacology, and disease.Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential.Interstitial deletion at 11q14.2-11q22.1 may cause severe learning difficulties, mental retardation and mild heart defects in 13-year old male.Evaluation of the effects of a metabotropic glutamate receptor 5-antagonist on electrically induced pain and central sensitization in healthy human volunteers.Development of PET and SPECT probes for glutamate receptors.Fragile X syndrome
P2860
Q24632814-70CD4386-7882-413C-9393-E6C8A0F62EEEQ30448534-D0020B58-6892-45D1-BE3A-9BA2888B766FQ30486477-4303846F-E421-451C-A941-AC4324C809E7Q34259468-2BE573AE-F37E-4E08-BD9A-B5365FBF4B5CQ34564332-B2F45122-9E4A-4019-956C-95D6FC9C1DDDQ34762404-914E7765-700A-4FF9-969A-6D312AB5ED85Q35663423-D23D069C-C36B-49DB-83C8-E4A1F0211D26Q35902157-CEA421D1-A95D-43D2-B42F-E4323412AE34Q36576250-8A319892-F034-4D6A-9B4E-C75D20F2E0A3Q36654331-4702DFAD-E613-4B13-873E-8BB1F2563661Q37061609-6FBAA9AF-5541-48BB-A0CF-A11097B0DDA4Q37280041-B3B8C756-2D96-4DE0-A6F2-17467D046A51Q37360436-6336F748-9B1F-4442-8CC5-2BE3D39EE88CQ37383094-03BE1536-3CCB-4705-A872-8B9F64C0C06DQ37420479-76CCC48C-BBFE-466C-8905-663DCDEAFEEDQ37670222-B871A8C8-2831-44D3-92B4-408B57FA9521Q37773480-3A66DECF-A9E2-4E12-80B2-BB439F2C5697Q42131092-A4F720AB-F63E-488E-8BF1-0D47D32ADF61Q44243936-97674362-464E-4F07-B12B-10B4C01F609AQ53015251-B4C16935-F234-4C3A-8CF8-1C75C53D4FECQ56091828-AE1012C0-AC83-460E-9168-382EFBACF97D
P2860
Recent advances in non-competitive mGlu5 receptor antagonists and their potential therapeutic applications.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Recent advances in non-competi ...... tial therapeutic applications.
@ast
Recent advances in non-competi ...... tial therapeutic applications.
@en
Recent advances in non-competi ...... tial therapeutic applications.
@nl
type
label
Recent advances in non-competi ...... tial therapeutic applications.
@ast
Recent advances in non-competi ...... tial therapeutic applications.
@en
Recent advances in non-competi ...... tial therapeutic applications.
@nl
prefLabel
Recent advances in non-competi ...... tial therapeutic applications.
@ast
Recent advances in non-competi ...... tial therapeutic applications.
@en
Recent advances in non-competi ...... tial therapeutic applications.
@nl
P2093
P356
P1476
Recent advances in non-competi ...... tial therapeutic applications.
@en
P2093
Abdelmalik Slassi
Alexander Minidis
David Wensbo
Donald McLeod
Edwin Johnson
Jan Mattsson
Karolina Nilsson
Lance G Hammerland
Louise Edwards
Methvin Isaac
P304
P356
10.2174/1568026054750236
P577
2005-01-01T00:00:00Z