mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo.
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Ligands that interact with putative MOR-mGluR5 heteromer in mice with inflammatory pain produce potent antinociception.Emotional Impairment and Persistent Upregulation of mGlu5 Receptor following Morphine Abstinence: Implications of an mGlu5-MOPr Interaction.Pharmacological Profiles of Oligomerized μ-Opioid Receptors.Contribution of heteromerization to G protein-coupled receptor function.mGluR5 is involved in proliferation of rat neural progenitor cells exposed to hypoxia with activation of mitogen-activated protein kinase signaling pathway.Synthesis and evaluation of 1,2,4-methyltriazines as mGluR5 antagonists.
P2860
mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 October 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
mGluR5 antagonists that block ...... nociceptive tolerance in vivo.
@en
mGluR5 antagonists that block ...... nociceptive tolerance in vivo.
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type
label
mGluR5 antagonists that block ...... nociceptive tolerance in vivo.
@en
mGluR5 antagonists that block ...... nociceptive tolerance in vivo.
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prefLabel
mGluR5 antagonists that block ...... nociceptive tolerance in vivo.
@en
mGluR5 antagonists that block ...... nociceptive tolerance in vivo.
@nl
P2093
P2860
P1433
P1476
mGluR5 antagonists that block ...... nociceptive tolerance in vivo.
@en
P2093
Bichoy H Gabra
F Ivy Carroll
Forrest L Smith
Hernán A Navarro
William L Dewey
P2860
P356
10.1016/J.BRAINRES.2007.10.007
P407
P577
2007-10-12T00:00:00Z