Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice. - Wikidata - awgldk - TriplyDB

Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.

Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.

http://www.wikidata.org/entity/Q34458051

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Host-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 protein An Evolutionary View of the Arms Race between Protein Kinase R and Large DNA Viruses CD8 T cells use IFN-γ to protect against the lethal effects of a respiratory poxvirus infection.Genomic expression libraries for the identification of cross-reactive orthopoxvirus antigens.Recombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses.Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication Virus infection rapidly activates the P58(IPK) pathway, delaying peak kinase activation to enhance viral replication.Comparative analysis of poxvirus orthologues of the vaccinia virus E3 protein: modulation of protein kinase R activity, cytokine responses, and virus pathogenicity Deletion of Fifteen Open Reading Frames from Modified Vaccinia Virus Ankara Fails to Improve Immunogenicity The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication Genomic Analysis, Phenotype, and Virulence of the Historical Brazilian Smallpox Vaccine Strain IOC: Implications for the Origins and Evolutionary Relationships of Vaccinia Virus Regulation of PACT-Mediated Protein Kinase Activation by the OV20.0 Protein of Orf Virus.Natural Killer Cells and Innate Interferon Gamma Participate in the Host Defense against Respiratory Vaccinia Virus Infection.Knockout of the Host Resistance Gene Pkr Fully Restores Replication of Murine Cytomegalovirus m142 and m143 Mutants In Vivo Essential role of protein kinase R antagonism by TRS1 in human cytomegalovirus replication.Variola virus E3L Zα domain, but not its Z-DNA binding activity, is required for PKR inhibition Interferon-stimulated genes: roles in viral pathogenesis.The NYCBH vaccinia virus deleted for the innate immune evasion gene, E3L, protects rabbits against lethal challenge by rabbitpox virus.An efficient method for generating poxvirus recombinants in the absence of selection Suppression of NYVAC Infection in HeLa Cells Requires RNase L but Is Independent of Protein Kinase R Activity.Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus.

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Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.

http://www.wikidata.org/entity/Q34458051

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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type

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

@ast

Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Journal of Virology

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Roles of vaccinia virus genes ...... eal infection of C57BL/6 mice.

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Jennifer E Embury

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Lyle L Moldawer

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Peter C Turner

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Richard W Moyer

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P2860

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Homologous regions of the alpha subunit of eukaryotic translational initiation factor 2 (eIF2alpha) and the vaccinia virus K3L gene product interact with the same domain within the dsRNA-activated protein kinase (PKR)

Antiviral actions of interferons

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

Evidence that vaccinia virulence factor E3L binds to Z-DNA in vivo: Implications for development of a therapy for poxvirus infection

A scientific journey through the 2-5A/RNase L system

A role for Z-DNA binding in vaccinia virus pathogenesis

Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response

PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons

Interferon-inducible antiviral effectors

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10.1128/JVI.00254-10

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