Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability - Wikidata - awgldk - TriplyDB

Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability

Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability

http://www.wikidata.org/entity/Q34463866

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Post-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetase The structure of alanyl-tRNA synthetase with editing domain Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization The C-Ala Domain Brings Together Editing and Aminoacylation Functions on One tRNA Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma The selective tRNA aminoacylation mechanism based on a single G•U pair The physiological target for LeuRS translational quality control is norvaline Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase.Trans-editing of mischarged tRNAs.Pre-transfer editing by class II prolyl-tRNA synthetase: role of aminoacylation active site in "selective release" of noncognate amino acids.Molecular biology: sticky end in protein synthesis An isolated class II aminoacyl-tRNA synthetase insertion domain is functional in amino acid editing p23H implicated as cis/trans regulator of AlaXp-directed editing for mammalian cell homeostasis A major determinant for binding and aminoacylation of tRNA(Ala) in cytoplasmic Alanyl-tRNA synthetase is mutated in dominant axonal Charcot-Marie-Tooth disease Revisiting the operational RNA code for amino acids: Ensemble attributes and their implications.Introduction of a leucine half-zipper engenders multiple high-quality crystals of a recalcitrant tRNA synthetase Severe oxidative stress induces protein mistranslation through impairment of an aminoacyl-tRNA synthetase editing site.Breaking sieve for steric exclusion of a noncognate amino acid from active site of a tRNA synthetase.Leucyl-tRNA synthetase from the ancestral bacterium Aquifex aeolicus contains relics of synthetase evolution.Molecular basis of alanine discrimination in editing site Aminoacyl transfer rate dictates choice of editing pathway in threonyl-tRNA synthetase.Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy.Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase.RNA recognition by designed peptide fusion creates "artificial" tRNA synthetase Mistranslation and its control by tRNA synthetases.Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons.Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific.Mechanism of tRNA-dependent editing in translational quality control Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation.Substrate specificity of bacterial prolyl-tRNA synthetase editing domain is controlled by a tunable hydrophobic pocket Structural analyses clarify the complex control of mistranslation by tRNA synthetases Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.Restoring species-specific posttransfer editing activity to a synthetase with a defunct editing domain Bacterial transfer RNAs.Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine.In vitro assays for the determination of aminoacyl-tRNA synthetase editing activity.Crystallization and preliminary X-ray crystallographic study of alanyl-tRNA synthetase from the archaeon Archaeoglobus fulgidus A freestanding proofreading domain is required for protein synthesis quality control in Archaea.

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P2860

Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability

http://www.wikidata.org/entity/Q34463866

description

2003 nî lūn-bûn

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2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի փետրվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Elucidation of tRNA-dependent ...... ignificance for cell viability

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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type

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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prefLabel

Elucidation of tRNA-dependent ...... ignificance for cell viability

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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The EMBO Journal

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Elucidation of tRNA-dependent ...... ignificance for cell viability

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P2093

Kirk Beebe

http://www.w3.org/2001/XMLSchema#string

Lluis Ribas De Pouplana

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Paul Schimmel

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P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site

Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin

Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase

Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase

Transfer RNA-mediated editing in threonyl-tRNA synthetase. The class II solution to the double discrimination problem

Enzyme structure with two catalytic sites for double-sieve selection of substrate

CAFASP-1: critical assessment of fully automated structure prediction methods

Phylogenies from molecular sequences: inference and reliability

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3

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22

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