about
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domainLRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complexInsight into the mode of action of the LRRK2 Y1699C pathogenic mutantMutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neuronsMutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson diseaseGenetics of Parkinson's diseaseMitochondrial Biology and Neurological DiseasesGenetics in Parkinson disease: Mendelian versus non-Mendelian inheritanceAnalysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2LRRK2 levels in immune cells are increased in Parkinson's diseaseLRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's diseaseGenetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.Imbalanced estrogen metabolism in the brain: possible relevance to the etiology of Parkinson's diseaseLRRK2 in Parkinson's disease and dementia with Lewy bodies.Heritability of Parkinson disease in Swedish twins: a longitudinal study.The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activityRISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis.Biomarkers for the diagnosis and management of Parkinson's disease.Gene therapy for Parkinson's disease: state-of-the-art treatments for neurodegenerative disease.Leucine-Rich Repeat Kinase (LRRK2) Genetics and Parkinson's Disease.The roles of non-coding RNAs in Parkinson's disease.Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.Rare Neurodegenerative Diseases: Clinical and Genetic Update.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Genetics of Parkinson's disease: LRRK2 on the rise.
@ast
Genetics of Parkinson's disease: LRRK2 on the rise.
@en
Genetics of Parkinson's disease: LRRK2 on the rise.
@nl
type
label
Genetics of Parkinson's disease: LRRK2 on the rise.
@ast
Genetics of Parkinson's disease: LRRK2 on the rise.
@en
Genetics of Parkinson's disease: LRRK2 on the rise.
@nl
prefLabel
Genetics of Parkinson's disease: LRRK2 on the rise.
@ast
Genetics of Parkinson's disease: LRRK2 on the rise.
@en
Genetics of Parkinson's disease: LRRK2 on the rise.
@nl
P2860
P356
P1433
P1476
Genetics of Parkinson's disease: LRRK2 on the rise.
@en
P2860
P304
P356
10.1093/BRAIN/AWH676
P407
P50
P577
2005-12-01T00:00:00Z