Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
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LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivoGermline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancersGermline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteriaGenes other than BRCA1 and BRCA2 involved in breast cancer susceptibilitySTK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreasOral Manifestations and Molecular Basis of Oral Genodermatoses: A Review.Update on our investigation of malignant tumors associated with Peutz-Jeghers syndrome in Japan.Integrin-binding protein nischarin interacts with tumor suppressor liver kinase B1 (LKB1) to regulate cell migration of breast epithelial cells.Spectrum of LKB1, EGFR, and KRAS mutations in chinese lung adenocarcinomas.High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.BRCA1 and BRCA2 mutations and treatment strategies for breast cancer.Inherited predisposition to pancreatic cancer.Genetic predisposition to colorectal cancer: where we stand and future perspectivesGermline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.Hereditary colorectal cancer: risk assessment and management.Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model.Translational advances regarding hereditary breast cancer syndromes.Clinical genetics of multiple endocrine neoplasias, Carney complex and related syndromes.10 rare tumors that warrant a genetics referral.The Peutz-Jeghers kinase LKB1 suppresses polyp growth from intestinal cells of a proglucagon-expressing lineage in miceSomatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndromeCorrelation of staining for LKB1 and COX-2 in hamartomatous polyps and carcinomas from patients with Peutz-Jeghers syndrome.Genotype-phenotype correlations in Peutz-Jeghers syndromeDe novo germline mutation in the serine-threonine kinase STK11/LKB1 gene associated with Peutz-Jeghers syndrome.A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.Nasal polyposis in Peutz-Jeghers syndrome: a distinct histopathological and molecular genetic entityThe epidemiology and pathogenesis of neoplasia in the small intestine.Epidemiology of cancer of the small intestineFindings from the Peutz-Jeghers syndrome registry of uruguay.Endopancreatic bile duct cholangiocarcinoma in a patient with peutz-jeghers syndrome.5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer.Treatment of resectable gastric cancer.Hereditary pancreatic and hepatobiliary cancersCancer risks in LKB1 germline mutation carriers.Genetics of breast cancer: a topic in evolution.Breast cancer genetics: unsolved questions and open perspectives in an expanding clinical practice.The hamartomatous polyposis syndromes: a clinical and molecular review.Clinical Application of Multigene Panels: Challenges of Next-Generation Counseling and Cancer Risk Management.Hereditary colorectal cancer syndromes.
P2860
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P2860
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@ast
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@en
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@nl
type
label
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@ast
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@en
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@nl
prefLabel
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@ast
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@en
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@nl
P2093
P1476
Increased risk for cancer in patients with the Peutz-Jeghers syndrome.
@en
P2093
Ahlquist DA
Boardman LA
Burgart LJ
Hartmann LC
McDonnell SK
Pittelkow M
Podratz KC
Thibodeau SN
P304
P356
10.7326/0003-4819-128-11-199806010-00004
P407
P577
1998-06-01T00:00:00Z