Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability.
about
Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis.Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitorsStructural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexesStructure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch SignalingNotch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesisThe extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney developmentNeuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airwaysBCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targetsDynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signalingThe canonical Notch signaling pathway: unfolding the activation mechanism.Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochleaNotch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblastsNotch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin.Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro.Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.A novel reporter of notch signalling indicates regulated and random Notch activation during vertebrate neurogenesis.Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.Notch dimerization is required for leukemogenesis and T-cell development.Notch inhibitors for cancer treatment.Two novel human NUMB isoforms provide a potential link between development and cancer.Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged miceTranscriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes.Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cellsTranscriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexesc-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster.Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch.Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo.Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription.Defining NOTCH3 target genes in ovarian cancer.SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers.Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesisReal-time imaging of notch activation with a luciferase complementation-based reporter.Overview of genetic tools and techniques to study Notch signaling in mice.Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2.Notch signaling mediates hypoxia-induced tumor cell migration and invasionMolecular insights into segmentation along the proximal-distal axis of the nephron.Mapping the consequence of Notch1 proteolysis in vivo with NIP-CREOct transcription factors in development and stem cells: insights and mechanisms.
P2860
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P2860
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Target selectivity of vertebra ...... rmines activation probability.
@ast
Target selectivity of vertebra ...... rmines activation probability.
@en
Target selectivity of vertebra ...... rmines activation probability.
@nl
type
label
Target selectivity of vertebra ...... rmines activation probability.
@ast
Target selectivity of vertebra ...... rmines activation probability.
@en
Target selectivity of vertebra ...... rmines activation probability.
@nl
prefLabel
Target selectivity of vertebra ...... rmines activation probability.
@ast
Target selectivity of vertebra ...... rmines activation probability.
@en
Target selectivity of vertebra ...... rmines activation probability.
@nl
P2093
P356
P1476
Target selectivity of vertebra ...... rmines activation probability.
@en
P2093
Chin-Tong Ong
Gary D Stormo
Hui-Teng Cheng
Li-Wei Chang
Raphael Kopan
Ryoichiro Kageyama
Toshiyuki Ohtsuka
P304
P356
10.1074/JBC.M506108200
P407
P577
2005-12-19T00:00:00Z