The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.
about
INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathwayRNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assemblyMonoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligaseRNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complexDNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2ATrue lies: the double life of the nucleotide excision repair factors in transcription and DNA repairWhat is the functional role of the thalidomide binding protein cereblon?A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machineryLentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycleGlobal-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo ModifiersXeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulationCullin family proteins and tumorigenesis: genetic association and molecular mechanismsImplication of posttranslational histone modifications in nucleotide excision repairNucleotide excision repair in eukaryotesThe emerging roles of ATP-dependent chromatin remodeling enzymes in nucleotide excision repairInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyDamaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repairCRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencingCullin-RING ubiquitin E3 ligase regulation by the COP9 signalosomeHistone ubiquitylation and its roles in transcription and DNA damage responseDistinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4BRegulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stressHistone ubiquitination associates with BRCA1-dependent DNA damage responseAccelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevityRegulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.Whole genome association studies of neuropsychiatric disease: An emerging era of collaborative genetic discovery.Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates.Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites.Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.DDB1 maintains genome integrity through regulation of Cdt1HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.Physical and functional interaction between DDB and XPA in nucleotide excision repair.Other proteins interacting with XP proteins.Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cellsMislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patientsDDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.CC3/TIP30 affects DNA damage repair.Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity.RETRACTED: DDB2, an essential mediator of premature senescence
P2860
Q24300346-2E3F5B8A-734D-4449-AD7B-505A815B8CB0Q24300428-A6531F2F-3A87-4050-A3C9-E7C333D8E2C9Q24305272-2C024D95-365F-4DC1-826A-19C667B488C3Q24309443-AE9D067A-3CE1-40AA-9931-83A0FD30FDC7Q24310859-B93D96CF-2F66-40B4-97FB-2A201295D576Q24546161-2FF05AE3-82E1-4954-8873-4C76DF7F38BEQ24596957-10D0E25A-08D4-4ABD-9EB5-1463FBF590F1Q24635072-E82A1937-CB72-4A38-A9E9-627C34B0F308Q24646885-44C92CC5-A273-45CE-B072-F0DFFBB1D5CDQ24680705-227B8F3E-5AEA-4F71-A742-F8E4C354D3EDQ26747331-B45F25F1-4E06-4042-A6BD-4E9DE603F805Q26777633-1DCBA5F5-DB61-4A42-8D9E-6C4F31DBBA59Q26822657-27C5E70C-0B65-4839-A1A8-E954B39DBE32Q26823794-DE1A4153-A4DD-4023-A853-CFAE07497664Q26850656-80787C86-8BF4-45C8-811B-9C21242F85D1Q26865871-4BBF4946-B106-44A4-89D7-F9A5417AD0ACQ27003218-6BA6D8A2-ADC4-49CF-B873-312B96EB75FFQ27670880-47CA0399-704E-4605-AA22-E787BB62528CQ27681419-72691D2C-D098-4A33-ABC0-C94892EAF5BCQ27704406-62D2CA5C-824C-418A-85E2-D3165F17E907Q28081194-F4BD85FE-1C4C-4693-B884-094A07CE949FQ28086765-0601876E-F5EE-40A4-845A-B672D4402C5DQ28472876-C0EF386B-8344-4421-BE04-03E1EF8376EDQ28506770-C3C79C24-5E91-4F0F-8F1F-3F2C4ACCB8EBQ28704343-1761EC99-D8DC-436A-80E7-059EF6A18072Q30411902-A0697D79-70F8-47F0-9094-CC86CA78FCF4Q30440018-1BCD888D-1AC6-47E1-8FDA-6C1DD88DE696Q30577983-6378719B-D171-4020-90CA-C5848423ABF8Q30854865-571CF68C-83C8-4E13-9382-878FBD73EB0FQ31144227-F6ACCE1A-C060-478B-8E07-D821888248F3Q33255742-F9538C77-1BF0-4540-94CB-19DE046D7158Q33290831-C3CD824E-F198-48EE-A7CB-9F506A502A14Q33389756-47114FF3-69E8-4273-8D63-D0E7952DFE85Q33404215-9F364E3B-FEF8-4510-A5C9-2BA54506166FQ33493863-C4779839-5266-4521-A6A7-4C725CA605F3Q33539726-9E387953-78FC-4A5F-B589-9FF6539EED8FQ33549610-2B34C238-9736-4739-9EBE-55A07BBB6C18Q33550605-4EBE24D1-C11E-462C-BFD4-76AD165E3571Q33557027-F8F0CF1E-278E-4894-8867-75CE6653939EQ33876992-36A28A0D-33F2-4988-A4A1-2D33F2A38652
P2860
The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@ast
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@en
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@nl
type
label
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@ast
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@en
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@nl
prefLabel
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@ast
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@en
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@nl
P2093
P2860
P356
P1476
The DDB1-CUL4ADDB2 ubiquitin l ...... e H2A at UV-damaged DNA sites.
@en
P2093
Arthur S Levine
Ching L Hsieh
Dawn C Bisi
Jennifer Guerrero-Santoro
Maria G Kapetanaki
Vesna Rapić-Otrin
P2860
P304
P356
10.1073/PNAS.0511160103
P407
P577
2006-02-10T00:00:00Z