Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study
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Temozolomide for high grade glioma14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2Induced Pluripotent Stem Cell as a New Source for Cancer ImmunotherapyMechanistic basis and clinical relevance of the role of transforming growth factor-β in cancerClinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathwayImmunosuppressive Mechanisms of Malignant Gliomas: Parallels at Non-CNS SitesInvolvement of long noncoding RNAs in diseases affecting the central nervous systemTherapeutic cancer vaccines: past, present, and futureExtracellular matrix as a contextual determinant of transforming growth factor-β signaling in epithelial-mesenchymal transition and in cancerTumor stroma as targets for cancer therapyComplexities of TGF-β targeted cancer therapy.TGF-β Signaling in Bone Remodeling and Osteosarcoma ProgressionImmunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?TGF-β signaling and its targeting for glioma treatmentDendritic Cell-Based Immunotherapy Treatment for Glioblastoma MultiformeConvection-Enhanced Delivery of Carboplatin PLGA Nanoparticles for the Treatment of GlioblastomaStrategies to improve delivery of anticancer drugs across the blood-brain barrier to treat glioblastoma.Neurosurgical oncology: advances in operative technologies and adjuncts.The roles of TGFβ in the tumour microenvironment.Strategies to use immune modulators in therapeutic vaccines against cancerNovel clinical therapeutics targeting the epithelial to mesenchymal transitionCancer association study of aminoacyl-tRNA synthetase signaling network in glioblastomaWnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.DiME: a scalable disease module identification algorithm with application to glioma progressionTargeting tumor cell motility to prevent metastasis.First-in-human dose study of the novel transforming growth factor-β receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma.Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer.Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer.Transforming growth factor-β pathway activity in glioblastoma.Current trends in targeted therapies for glioblastoma multiformeTherapeutic cancer vaccines: current status and moving forward.Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma.TGF-β1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT)Immunosuppressive mechanisms in glioblastoma.Exploring the key genes and signaling transduction pathways related to the survival time of glioblastoma multiforme patients by a novel survival analysis model.TGF-ß isoforms in cancer: Immunohistochemical expression and Smad-pathway-activity-analysis in thirteen major tumor types with a critical appraisal of antibody specificity and immunohistochemistry assay validity.Targeting the TGFβ signalling pathway in disease.Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.Comparison of pulsed versus continuous convective flow for central nervous system tissue perfusion: laboratory investigation.Therapeutic potential of targeting microRNA-10b in established intracranial glioblastoma: first steps toward the clinic.
P2860
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P2860
Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeted therapy for high-grad ...... and controlled phase IIb study
@ast
Targeted therapy for high-grad ...... and controlled phase IIb study
@en
Targeted therapy for high-grad ...... and controlled phase IIb study
@nl
type
label
Targeted therapy for high-grad ...... and controlled phase IIb study
@ast
Targeted therapy for high-grad ...... and controlled phase IIb study
@en
Targeted therapy for high-grad ...... and controlled phase IIb study
@nl
prefLabel
Targeted therapy for high-grad ...... and controlled phase IIb study
@ast
Targeted therapy for high-grad ...... and controlled phase IIb study
@en
Targeted therapy for high-grad ...... and controlled phase IIb study
@nl
P2093
P2860
P356
P1433
P1476
Targeted therapy for high-grad ...... and controlled phase IIb study
@en
P2093
A Balasubramaniam
A K Mahapatra
G Stockhammer
H Heinrichs
I Poverennova
K-H Schlingensiepen
N K Venkataramana
P Jachimczak
P2860
P304
P356
10.1093/NEUONC/NOQ142
P50
P577
2010-10-27T00:00:00Z