Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.

Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.

Item
http://www.wikidata.org/entity/Q34481483
Balkan endemic nephropathy: an update on its aetiologyCytochrome P450 1A2 detoxicates aristolochic acid in the mouse.An exploratory evaluation of the utility of transcriptional and urinary kidney injury biomarkers for the prediction of aristolochic acid-induced renal injury in male rats.Physiological and molecular characterization of aristolochic acid transport by the kidneyBioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.Aristolochic acid I metabolism in the isolated perfused rat kidney.A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acidActive Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1.Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivoRole of hepatic cytochrome P450 enzymes in the detoxication of aristolochic acid I; effects on DNA adduct, mutation, and tumor formationSulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease.Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid.Naturally occurring aristolochic acid analogues and their toxicities.Localization of aristolochic acid in mouse kidney tissues by immunohistochemistry using an anti-AA-I and AA-II monoclonal antibody.DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer.
P2860

Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.

Item
http://www.wikidata.org/entity/Q34481483
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@ast
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@en
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@nl
type
label
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@ast
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@en
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@nl
prefLabel
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@ast
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@en
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Detoxification of aristolochic ...... istolochic acid Ia in rodents.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932