Identification of the separate domains in the hepatic glycogen-targeting subunit of protein phosphatase 1 that interact with phosphorylase a, glycogen and protein phosphatase 1.
about
Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signalsCounteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein PhosphatasesMolecular recognition of the protein phosphatase 1 glycogen targeting subunit by glycogen phosphorylaseThe level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved ratsFasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesisMutations of the serine phosphorylated in the protein phosphatase-1-binding motif in the skeletal muscle glycogen-targeting subunitGlycogen synthase association with the striated muscle glycogen-targeting subunit of protein phosphatase-1. Synthase activation involves scaffolding regulated by beta-adrenergic signaling.PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistanceGlycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus.Regulation of glucose homeostasis and lipid metabolism by PPP1R3G-mediated hepatic glycogenesisPhosphorylation of the skeletal muscle glycogen-targetting subunit of protein phosphatase 1 in response to adrenaline in vivo.Identification of binding sites on protein targeting to glycogen for enzymes of glycogen metabolism.A whole-body model for glycogen regulation reveals a critical role for substrate cycling in maintaining blood glucose homeostasis.Central role for protein targeting to glycogen in the maintenance of cellular glycogen stores in 3T3-L1 adipocytes.Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.Defective glycogenesis contributes toward the inability to suppress hepatic glucose production in response to hyperglycemia and hyperinsulinemia in zucker diabetic fatty ratsImpact of a glycogen phosphorylase inhibitor and metformin on basal and glucagon-stimulated hepatic glucose flux in conscious dogsExercise training-induced adaptations associated with increases in skeletal muscle glycogen content.The twentieth century struggle to decipher insulin signalling.Glycogen and its metabolism: some new developments and old themes.Differential regulation of glycogenolysis by mutant protein phosphatase-1 glycogen-targeting subunits.AMP-activated protein kinase--a sensor of glycogen as well as AMP and ATP?Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance.Solution structure of family 21 carbohydrate-binding module from Rhizopus oryzae glucoamylase.Serine/Threonine Phosphatases in Atrial Fibrillation.Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure.Structure of the human glycogen-associated protein phosphatase 1 regulatory subunit hGM: homology modeling revealed an (alpha/beta)8-barrel-like fold in the multidomain protein.Protein targeting to glycogen overexpression results in the specific enhancement of glycogen storage in 3T3-L1 adipocytes.Expression and glycogenic effect of glycogen-targeting protein phosphatase 1 regulatory subunit GL in cultured human muscleRegulation of glycogen metabolism in cultured human muscles by the glycogen phosphorylase inhibitor CP-91149.Novel therapeutics based on inhibiting the interaction of glycogen phosphorylase and GL-subunit of glycogen-associated protein phosphatase 1: WO2009127723.Hepatic glycogen synthesis is highly sensitive to phosphorylase activity: evidence from metabolic control analysis.Inactivation of phosphorylase is a major component of the mechanism by which insulin stimulates hepatic glycogen synthesis.Development of a colorimetric and a fluorescence phosphatase-inhibitor assay suitable for drug discovery approaches.Association of PPP1R3B polymorphisms with blood lipid and C-reactive protein levels in a Chinese population (PPP1R3B C ).A unique polypeptide from the C-terminus of the exocellular esterase of Acinetobacter venetianus RAG-1 modulates the emulsifying activity of the polymeric bioemulsifier apoemulsan.Relationship between Genetic Variation at PPP1R3B and Liver Glycogen and Triglyceride Levels.Overexpression of protein targeting to glycogen in cultured human muscle cells stimulates glycogen synthesis independent of glycogen and glucose 6-phosphate levels.Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes.
P2860
Q24301131-123EB20B-1CB0-4939-BF44-F2B520D120F9Q24306423-3A2215F0-0B7C-4A7D-B67C-52DE58E58F22Q26776182-CD184895-CBFF-4E53-8BDC-0B34C2C0F90AQ27649540-8CED2A3B-A4FE-4E9D-8252-5FC0247D75BDQ28364671-CF9AA41E-B93F-4EC0-8F21-B5DF5936F10AQ28591340-B813DC32-C587-4383-95B6-6BA2ED82DB23Q30304658-DECBA39E-BC45-45FF-A1F5-E849BEB3ECF2Q30305751-276CE765-BFE3-404F-88AA-ED7FE13B7E39Q30453008-40EA00A4-AD8D-4B6C-954A-D8F67E244ED9Q32066328-B49D0A2D-741A-46F0-97D5-568415639F46Q33663648-2BA77573-C5AE-4C34-AC63-D7DEC827A20AQ33887873-8B2E068D-DA58-477B-B7AA-3E9A32A4A9FDQ33913304-99C6B334-ED80-4AFB-BBCE-2BE6C0166F75Q34098022-1793CEBD-9D96-4660-91E5-79FC20B17AC7Q34233398-3C4BBA6A-EE5B-4A5C-AE58-F97BCFCB5410Q34729631-827BB9A6-CE37-4BDB-9193-ED2C0C951B7EQ35180025-B15894F7-D50E-43D3-9618-3A5ADBE9D798Q35516372-628C88E7-8E46-4311-8D3B-F016E3D9BB10Q36572733-A271CB79-A317-4AEF-8339-A45F4AD3E0C4Q36631664-AF2571F4-A6F2-4C32-9EE6-0A2825AC55FFQ37095413-F60736ED-D5C9-4702-87E7-B76D6C529E81Q37339343-DB8B7124-832F-42FF-BB1E-040F454E8647Q37401922-14142DC9-DBAF-4535-B27E-569206B37E54Q38165106-A3E08471-EC0C-4D1E-A9E3-7A5A196AC89BQ38307453-F05EB98A-AF84-4B3D-800E-43E829DE0B57Q38771731-2D44ED7D-66FB-4A51-8E5F-4D83495E1C38Q41824865-C373FA88-D7FF-487E-B552-8D440D12B5F5Q42247894-018D2346-F3C3-4AC1-A3AF-CA92E5F0355AQ42442963-669BF2D6-E39D-4974-8D12-EB2E1A6A8373Q42529048-A36355EF-F363-494A-8BDA-808E0E2C733BQ43003595-091D5C69-30E2-42C6-8D94-E9626E41FCA3Q43109523-77037C18-E41D-478F-9E4A-B9DC1D714663Q43579828-47D9F110-D504-4A69-83EC-062B16D7CF0EQ44489227-D3B05D66-0842-4135-A2C1-26740F868961Q44874960-1AF7CEBE-E097-4194-BCFB-9CF0C9995D2BQ45717037-261CD6FE-2ED5-48BC-AE8F-4A399478F1B7Q46764358-A96A81FA-2ECD-44B9-AC08-BAE2D3E95CA9Q47265933-DAD84165-5941-4A39-8299-88280F7D66AAQ47620271-3443777D-5614-4912-8C34-9D828E2F6088Q47620818-5B7BB6FB-4280-43BF-B2D1-FC413FB04286
P2860
Identification of the separate domains in the hepatic glycogen-targeting subunit of protein phosphatase 1 that interact with phosphorylase a, glycogen and protein phosphatase 1.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Identification of the separate ...... gen and protein phosphatase 1.
@ast
Identification of the separate ...... gen and protein phosphatase 1.
@en
Identification of the separate ...... gen and protein phosphatase 1.
@nl
type
label
Identification of the separate ...... gen and protein phosphatase 1.
@ast
Identification of the separate ...... gen and protein phosphatase 1.
@en
Identification of the separate ...... gen and protein phosphatase 1.
@nl
prefLabel
Identification of the separate ...... gen and protein phosphatase 1.
@ast
Identification of the separate ...... gen and protein phosphatase 1.
@en
Identification of the separate ...... gen and protein phosphatase 1.
@nl
P2093
P2860
P356
P1433
P1476
Identification of the separate ...... gen and protein phosphatase 1.
@en
P2093
Armstrong CG
Doherty MJ
P2860
P304
P356
10.1042/BJ3360699
P407
P478
336 ( Pt 3)
P577
1998-12-01T00:00:00Z