Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes.
about
Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signalsMolecular recognition of the protein phosphatase 1 glycogen targeting subunit by glycogen phosphorylaseLaforin, a dual specificity phosphatase that dephosphorylates complex carbohydratesThe muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exerciseThe level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved ratsHepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liverContributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa ratsFasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesisInsulin control of glycogen metabolism in knockout mice lacking the muscle-specific protein phosphatase PP1G/RGL.Differential pattern of glycogen accumulation after protein phosphatase 1 glycogen-targeting subunit PPP1R6 overexpression, compared to PPP1R3C and PPP1R3A, in skeletal muscle cells.Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity.Central role for protein targeting to glycogen in the maintenance of cellular glycogen stores in 3T3-L1 adipocytes.Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.Glycogen Repletion in Brown Adipose Tissue upon Refeeding Is Primarily Driven by Phosphorylation-Independent MechanismsAdipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans.Insights from Genome-Wide Association Analyses of Nonalcoholic Fatty Liver Disease.Differential regulation of glycogenolysis by mutant protein phosphatase-1 glycogen-targeting subunits.Stranger in a strange land: roles of glycogen turnover in adipose tissue metabolism.Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter.Hypoxia-inducible factor 1-mediated regulation of PPP1R3C promotes glycogen accumulation in human MCF-7 cells under hypoxia.Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway.Protein targeting to glycogen overexpression results in the specific enhancement of glycogen storage in 3T3-L1 adipocytes.Generation of a dominant-negative glycogen targeting subunit for protein phosphatase-1.Transgenic overexpression of protein targeting to glycogen markedly increases adipocytic glycogen storage in mice.Expression and glycogenic effect of glycogen-targeting protein phosphatase 1 regulatory subunit GL in cultured human muscleDifferential modulation of 3T3-L1 adipogenesis mediated by 11beta-hydroxysteroid dehydrogenase-1 levels.Regulation of glycogen metabolism in cultured human muscles by the glycogen phosphorylase inhibitor CP-91149.Glycogen-targeting subunits and glucokinase differentially affect pathways of glycogen metabolism and their regulation in hepatocytes.Reversal of diet-induced glucose intolerance by hepatic expression of a variant glycogen-targeting subunit of protein phosphatase-1.Hepatic expression of a targeting subunit of protein phosphatase-1 in streptozotocin-diabetic rats reverses hyperglycemia and hyperphagia despite depressed glucokinase expression.Inactivation of phosphorylase is a major component of the mechanism by which insulin stimulates hepatic glycogen synthesis.The glycogenic action of protein targeting to glycogen in hepatocytes involves multiple mechanisms including phosphorylase inactivation and glycogen synthase translocation.Association of PPP1R3B polymorphisms with blood lipid and C-reactive protein levels in a Chinese population (PPP1R3B C ).Relationship between Genetic Variation at PPP1R3B and Liver Glycogen and Triglyceride Levels.Overexpression of protein targeting to glycogen in cultured human muscle cells stimulates glycogen synthesis independent of glycogen and glucose 6-phosphate levels.Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis.Association between the PPP1R3B polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke in a southern Chinese Han population.
P2860
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P2860
Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Distinctive regulatory and met ...... RGl) expressed in hepatocytes.
@en
Distinctive regulatory and met ...... RGl) expressed in hepatocytes.
@nl
type
label
Distinctive regulatory and met ...... RGl) expressed in hepatocytes.
@en
Distinctive regulatory and met ...... RGl) expressed in hepatocytes.
@nl
prefLabel
Distinctive regulatory and met ...... RGl) expressed in hepatocytes.
@en
Distinctive regulatory and met ...... RGl) expressed in hepatocytes.
@nl
P2093
P2860
P356
P1476
Distinctive regulatory and met ...... RGl) expressed in hepatocytes.
@en
P2093
P2860
P304
26396-26403
P356
10.1074/JBC.M002427200
P407
P577
2000-08-01T00:00:00Z