Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region.
about
Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast CarcinomaEts-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoterRegulation of BRCA1 expression and its relationship to sporadic breast cancerOncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryDecreased BRCA1 confers tamoxifen resistance in breast cancer cells by altering estrogen receptor-coregulator interactions.BRCA1 represses amphiregulin gene expression.Epigenetically silenced PTPRO functions as a prognostic marker and tumor suppressor in human lung squamous cell carcinoma.Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens.Emerging roles of BRCA1 alternative splicing.MTA1-mediated transcriptional repression of BRCA1 tumor suppressor geneBasal-like breast cancer displays distinct patterns of promoter methylationRegulation of BRCA1 transcription by specific single-stranded DNA binding factorsPromoter methylation and expression changes of BRCA1 in cancerous tissues of patients with sporadic breast cancer.The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release.Epigenomics of ovarian cancer and its chemoprevention.Depletion of eIF2·GTP·Met-tRNAi translation initiation complex up-regulates BRCA1 expression in vitro and in vivo.Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ERα-negative breast tumorigenesisTargeting Brn-3b in breast cancer therapy.BRCA1 epigenetic inactivation predicts sensitivity to platinum-based chemotherapy in breast and ovarian cancer.Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1α, autophagy and ketone body productionDynamic interactions between the promoter and terminator regions of the mammalian BRCA1 geneBRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.A mammary-specific, long-range deletion on mouse chromosome 11 accelerates Brca1-associated mammary tumorigenesis.Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycleOpportunities and hurdles in the treatment of BRCA1-related breast cancer.Epigenetics of breast cancer: Modifying role of environmental and bioactive food compounds.Aberrant DNA methylation status of DNA repair genes in breast cancer treated with neoadjuvant chemotherapy.BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays.BRCA1 interacts with poly(A)-binding protein: implication of BRCA1 in translation regulation.Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines.A somatic mutation in the 5'UTR of BRCA1 gene in sporadic breast cancer causes down-modulation of translation efficiency.BRCA1 dysfunction in sporadic basal-like breast cancer.Identification of BRCA1-IRIS, a BRCA1 locus product.Identification of a novel transcriptional repressor element located in the first intron of the human BRCA1 gene.Gestational exposure to the AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin induces BRCA-1 promoter hypermethylation and reduces BRCA-1 expression in mammary tissue of rat offspring: preventive effects of resveratrol.A CREB site in the BRCA1 proximal promoter acts as a constitutive transcriptional element.Reduced Brca1 protein expression in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary carcinomas.Impact of Etoposide on BRCA1 Expression in Various Breast Cancer Cell Lines.
P2860
Q22242224-CEFE9418-CBD9-4641-85BA-76993D514EE2Q24297834-04F83AC6-DF81-46C3-87C2-CF44F8C5D2EAQ24795166-B5F17C09-E6D7-43EC-B48D-3A540E204DB3Q26851813-EFE1A584-35F1-40A5-9D25-86A808312295Q30439093-AD4229A0-141E-4F52-8819-0DD02A7585E2Q33630913-AEB3551C-D21B-4720-9808-7790297A70FBQ33828327-B56C3403-CAB7-4829-92BE-569C7ED8A7C3Q33915724-530AE432-0E02-4467-9D94-8C0FBD66E88DQ33919195-1831E5C1-0430-4DE4-8F03-FFF058F68485Q34699428-103BBFE7-A833-42C4-997E-4C3C67FAFC5CQ34982503-E0B4CC03-386D-4875-9680-68249A8780E4Q35002431-D51C4E12-77CE-4AB2-B1A8-D4B9ACDCE6B3Q35167715-F52AB409-3AA9-4915-AC69-F8022E7BF888Q35172714-D007CE4C-EE8D-4DDC-9577-6A544B5D565DQ35711392-7A396DCA-A7CD-42E3-A44F-15E9C8E12D8EQ35740103-E8BCA39E-BDFA-471E-B78F-D1BECE0ED1EDQ35749504-CA2DEAE6-4CD9-4567-BC33-7F0B53AD888CQ35860006-97D80BEB-DA44-4C46-98AE-4CCF6176F95CQ35881326-2C3B887D-18AA-40D2-B47D-CD19DB11E294Q36379362-8791D133-2F44-4F42-BEE7-2E5709386178Q36402747-332C1BC9-B32D-4A79-88BE-6225AE4A79D2Q36472238-0EB6CB30-259B-45C9-84FE-F42B6E59FF0FQ36516089-AF6E86C0-89E8-4E3A-A63F-A5E07ECD2D58Q36556331-B33F839A-7AA4-497A-9A01-37853BABA877Q36982090-E192A6A1-CDB7-4902-9796-76301254BA3AQ37271818-F2A0C9E5-8E57-4F07-9968-3D2AC8F3FDA7Q38129725-8BD0E9D9-F3A8-42EF-8FA7-BA3DA9A266F6Q38825290-0B21F891-8A15-4065-8887-00BF4000D70FQ39019991-A05E2455-4A1B-4D85-B731-BC961EA01CBEQ40061315-0D39E888-6BAF-499A-891F-3385648A6A71Q40266057-EBFA0302-1F91-412A-9EF9-C52A4A5D7E95Q40749668-C6DA08B0-8183-493E-87F3-8B6B1357D1AEQ40787469-A7C4ECB2-5BEF-45A1-BDC7-39613C3E9EF3Q42502209-E2BE2D82-87F0-47E9-A51C-62E0C79046F0Q42636849-0331EFF5-CBD8-4D42-9ED7-3EAB9929B8ECQ42647919-E328A47F-5C43-4EFC-BCBA-B19191E3ECB5Q42708863-E57BAC5F-0488-4D17-92B7-E831ECBD3711Q43796901-C8D74BB2-B7C4-45E6-B7BA-DD1F2B1E2085Q44119819-C4C8EC14-9040-4819-8CA8-C13A43C313F7Q47097943-AF7D54E0-8179-4E5A-8D10-92FCD5062AA2
P2860
Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@ast
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@en
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@nl
type
label
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@ast
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@en
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@nl
prefLabel
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@ast
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@en
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@nl
P2093
P356
P1433
P1476
Down-regulation of BRCA1 in hu ...... the putative promoter region.
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1202248
P407
P577
1998-12-01T00:00:00Z
P5875
P6179
1030949607