F200A substitution in the third transmembrane helix of human cannabinoid CB1 receptor converts AM2233 from receptor agonist to inverse agonist.

F200A substitution in the third transmembrane helix of human cannabinoid CB1 receptor converts AM2233 from receptor agonist to inverse agonist.

Item
http://www.wikidata.org/entity/Q34488504
Understanding functional residues of the cannabinoid CB1.Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation.hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation.Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown.Cannabinoid-1 receptor inverse agonists: current understanding of mechanism of action and unanswered questions.Identification of essential cannabinoid-binding domains: structural insights into early dynamic events in receptor activationCannabinoid receptors: nomenclature and pharmacological principlesEvaluating cellular impedance assays for detection of GPCR pleiotropic signaling and functional selectivity.Distinct second extracellular loop structures of the brain cannabinoid CB(1) receptor: implication in ligand binding and receptor function
P2860

F200A substitution in the third transmembrane helix of human cannabinoid CB1 receptor converts AM2233 from receptor agonist to inverse agonist.

Item
http://www.wikidata.org/entity/Q34488504
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
F200A substitution in the thir ...... or agonist to inverse agonist.
@ast
F200A substitution in the thir ...... or agonist to inverse agonist.
@en
F200A substitution in the thir ...... or agonist to inverse agonist.
@nl
type
label
F200A substitution in the thir ...... or agonist to inverse agonist.
@ast
F200A substitution in the thir ...... or agonist to inverse agonist.
@en
F200A substitution in the thir ...... or agonist to inverse agonist.
@nl
prefLabel
F200A substitution in the thir ...... or agonist to inverse agonist.
@ast
F200A substitution in the thir ...... or agonist to inverse agonist.
@en
F200A substitution in the thir ...... or agonist to inverse agonist.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
F200A substitution in the thir ...... or agonist to inverse agonist.
@en
P2093
P304
P31
P356
10.1016/J.EJPHAR.2005.12.026
P407
P433
P478
P577
P698
P921