Evaluating cellular impedance assays for detection of GPCR pleiotropic signaling and functional selectivity.
about
Gaddum Memorial Lecture 2014: receptors as an evolving concept: from switches to biased microprocessorsProresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolventIdentification of resolvin D2 receptor mediating resolution of infections and organ protectionHuman and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonistsImpedance responses reveal β₂-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profilesLabel-free integrative pharmacology on-target of opioid ligands at the opioid receptor familyA simple method for quantifying functional selectivity and agonist biasSeven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Ligand-dependent conformations and dynamics of the serotonin 5-HT(2A) receptor determine its activation and membrane-driven oligomerization propertiesStructural determinants in the second intracellular loop of the human cannabinoid CB1 receptor mediate selective coupling to G(s) and G(i)Label-Free Receptor Assays.The significance of G protein-coupled receptor crystallography for drug discovery.Novel tail and head group prostamide probesResolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.Gsα deficiency in the paraventricular nucleus of the hypothalamus partially contributes to obesity associated with Gsα mutationsDevelopment of a test that measures real-time HER2 signaling function in live breast cancer cell lines and primary cells.G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortinsConformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective.Development of functionally selective, small molecule agonists at kappa opioid receptors.Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders.Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.Label-free screening assays: a strategy for finding better drug candidates.Functional selectivity of adenosine receptor ligandsLigand functional selectivity and quantitative pharmacology at G protein-coupled receptors.An update of novel screening methods for GPCR in drug discovery.Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology.Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation.Biased agonism.Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements.Cell-based assay protocol for the prognostic prediction of idiopathic scoliosis using cellular dielectric spectroscopy.Functional efficacy of adenosine A₂A receptor agonists is positively correlated to their receptor residence timeNeuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus.Succinate receptor GPR91, a Gα(i) coupled receptor that increases intracellular calcium concentrations through PLCβ.The development of label-free cellular assays for drug discovery.Label-Free Dynamic Mass Redistribution and Bio-Impedance Methods for Drug Discovery.New maresin conjugates in tissue regeneration pathway counters leukotriene D4-stimulated vascular responses.Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1-CB2 Heteroreceptor Complexes.Label-Free Biosensors for Cell Biology
P2860
Q27005640-7DBC642A-F60E-4DAF-922B-C8E5F394C371Q28258840-E4B5E653-2957-4B16-9861-413B7E4E4E1DQ28265395-F6BC3B90-D1C6-46C5-BB8B-6DE2954EB7FCQ28278805-EE71DB09-C4CC-403D-8F8E-5FABBAFFC688Q28478728-3A82C244-097F-4874-9B3F-9446771E6FAAQ28709650-E7DBD86F-F896-43C2-8255-DF4B0D4D1032Q28728741-DC23C0FD-2937-43FC-8116-1B0222C11C9EQ33890786-CC88ABE4-42DF-48BE-89E2-D66C8AC8B0E7Q34244869-4E056AC8-EED1-4E63-AF5A-C64B60D0FC1EQ34442426-8604C7BD-B54C-4EF3-BDFF-46381774DD94Q34473007-EE5AFA5F-CD16-4A3B-B289-E01A1500861DQ35264433-02A4D567-AFC9-4DA5-99FD-B7FA1B7F3816Q35508809-61CBE9C0-C373-4BB4-BC17-0444C3CA6B3DQ35951840-4756A610-7C11-4FD8-964A-23B95CE2D30AQ36177456-D2B97918-2C41-4118-8AAE-17269A899D0BQ36311216-93CA571B-0893-417B-81B8-2E622CC48A3AQ36430707-FAD3BF1B-501C-44BC-BE4D-A7EE2A4A5DB0Q36941174-68B72741-B735-40FC-BD04-0F0B25CFD295Q37405071-29FED13B-5E75-44C2-AA48-DB96C48C4CC1Q37416470-A52CF7D3-6823-438B-947F-39DD749F7757Q37610141-7CE40626-A65D-4ECB-9C10-55D5A7CC45E6Q37856304-0AA9B6A7-69B3-4AD8-8B96-368A20282578Q37872220-3A3C27CA-4885-44A6-9431-3AAD274A67C0Q38014954-C994C6CD-BF87-4DE9-9D53-4177060D2ABEQ38020237-A79C5A59-D906-422A-A4A2-36973F38AAE4Q39660780-A329C3E5-1621-4603-9CD7-AF308B5DEF61Q40473067-A1B505CF-6EC2-4609-871B-6B464BD166F2Q41863995-1E019C98-7757-417C-8B34-52E862E29DE1Q41865415-89950633-42E3-4103-8C2C-E7FE45BA4A59Q41993101-BF6FF78F-0566-4A7A-8BE5-41698D0B5FA1Q42246408-3E345BA4-F8AA-4D71-ABDF-BAD3F7C43EF5Q44195848-DF5D2BC2-2997-4C00-99D2-962E73DD4091Q45959379-01448A74-B21A-44FE-8386-C112217B7FFEQ47685791-39A68155-EDBD-45E4-9784-2486730E29E0Q50569577-77BCF778-B6F8-45B0-AA41-1174F58D2A02Q52681249-002987C8-6796-448F-971E-EADA5021B9A4Q55513558-2F4EF00B-0898-42E9-B2A5-E3EB455C6428Q58687097-EEC8C5C2-977B-4453-9A36-3A5E0CF8092F
P2860
Evaluating cellular impedance assays for detection of GPCR pleiotropic signaling and functional selectivity.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Evaluating cellular impedance ...... ng and functional selectivity.
@en
Evaluating cellular impedance ...... ng and functional selectivity.
@nl
type
label
Evaluating cellular impedance ...... ng and functional selectivity.
@en
Evaluating cellular impedance ...... ng and functional selectivity.
@nl
prefLabel
Evaluating cellular impedance ...... ng and functional selectivity.
@en
Evaluating cellular impedance ...... ng and functional selectivity.
@nl
P2860
P356
P1476
Evaluating cellular impedance ...... ng and functional selectivity.
@en
P2093
Clay W Scott
Matthew F Peters
P2860
P304
P356
10.1177/1087057108330115
P577
2009-02-11T00:00:00Z