Limits of ligand selectivity from docking to models: in silico screening for A(1) adenosine receptor antagonists
about
Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congenersStructure-based approaches to ligands for G-protein-coupled adenosine and P2Y receptors, from small molecules to nanoconjugates.Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.Structure-Based Virtual Screening for Dopamine D2 Receptor Ligands as Potential Antipsychotics.An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2.New paradigms in GPCR drug discovery.Muscarinic receptors as model targets and antitargets for structure-based ligand discovery.Predicting Subtype Selectivity for Adenosine Receptor Ligands with Three-Dimensional Biologically Relevant Spectrum (BRS-3D).Crystal structures of the A2A adenosine receptor and their use in medicinal chemistry.Dynamic behavior of the active and inactive states of the adenosine A(2A) receptor.Coumarins and adenosine receptors: New perceptions in structure-affinity relationships.Structural Probing and Molecular Modeling of the A₃ Adenosine Receptor: A Focus on Agonist Binding.Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models.Discovery of new GPCR ligands to illuminate new biology.Breakthrough in GPCR Crystallography and Its Impact on Computer-Aided Drug Design.Discovery of the first A1 adenosine receptor ligand based on the chromone scaffold
P2860
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P2860
Limits of ligand selectivity from docking to models: in silico screening for A(1) adenosine receptor antagonists
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Limits of ligand selectivity from docking to models: in silico screening for A
@nl
Limits of ligand selectivity f ...... adenosine receptor antagonists
@ast
Limits of ligand selectivity f ...... adenosine receptor antagonists
@en
type
label
Limits of ligand selectivity from docking to models: in silico screening for A
@nl
Limits of ligand selectivity f ...... adenosine receptor antagonists
@ast
Limits of ligand selectivity f ...... adenosine receptor antagonists
@en
prefLabel
Limits of ligand selectivity from docking to models: in silico screening for A
@nl
Limits of ligand selectivity f ...... adenosine receptor antagonists
@ast
Limits of ligand selectivity f ...... adenosine receptor antagonists
@en
P2860
P50
P1433
P1476
Limits of ligand selectivity f ...... adenosine receptor antagonists
@en
P2093
Adam C Marko
P2860
P304
P356
10.1371/JOURNAL.PONE.0049910
P407
P577
2012-11-21T00:00:00Z