Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers - Wikidata - awgldk - TriplyDB

Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers

Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers

http://www.wikidata.org/entity/Q34491947

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Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer APOBEC3B, a molecular driver of mutagenesis in human cancers.Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation.Oxidative Reactivities of 2-Furylquinolines: Ubiquitous Scaffolds in Common High-Throughput Screening Libraries.APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer.The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B.Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers.Progressive APOBEC3B mRNA expression in distant breast cancer metastases.Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.A novel gene expression signature for bone metastasis in breast carcinomas.PrimPol prevents APOBEC/AID family mediated DNA mutagenesis The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif Pharmacogenomic considerations in the treatment of muscle-invasive bladder cancer.Increased APOBEC3B Predicts Worse Outcomes in Lung Cancer: A Comprehensive Retrospective Study APOBEC3G Expression Correlates with T-Cell Infiltration and Improved Clinical Outcomes in High-grade Serous Ovarian Carcinoma APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma.APOBEC3B high expression status is associated with aggressive phenotype in Japanese breast cancers.Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population.p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers APOBEC Enzymes as Targets for Virus and Cancer Therapy.Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European population.Understanding the regulation of APOBEC3 expression: Current evidence and much to learn.APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution.Viral subversion of APOBEC3s: Lessons for anti-tumor immunity and tumor immunotherapy.Tumour heterogeneity and resistance to cancer therapies.Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.MutationalPatterns: comprehensive genome-wide analysis of mutational processes.APOBEC3B up-regulation independently predicts ovarian cancer prognosis: a cohort study.Q58714444

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Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers

http://www.wikidata.org/entity/Q34491947

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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type

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Hormones and Cancer

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Elevated APOBEC3B correlates w ...... ceptor-positive breast cancers

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Anieta M Sieuwerts

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Brian Leyland-Jones

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John W M Martens

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Marion E Meijer-Van Gelder

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Maxime P Look

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P2860

First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G

Mutational processes molding the genomes of 21 breast cancers

BioJava: an open-source framework for bioinformatics in 2012

Comprehensive molecular portraits of human breast tumours

Complex landscapes of somatic rearrangement in human breast cancer genomes.

The APOBEC3 family of retroelement restriction factors

A gene-expression signature as a predictor of survival in breast cancer

Molecular portraits of human breast tumours

Signatures of mutational processes in human cancer

Patterns of somatic mutation in human cancer genomes

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