Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system. - Wikidata - awgldk - TriplyDB

Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system.

Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system.

http://www.wikidata.org/entity/Q34497857

about

Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and Beyond Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype Localised intravascular coagulation complicating venous malformations in children: Associations and therapeutic options.Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island.Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.Differential Regulation of Cardiac Function and Intracardiac Cytokines by Rapamycin in Healthy and Diabetic Rats.Intermittent Fasting Preserves Beta-Cell Mass in Obesity-induced Diabetes via the Autophagy-Lysosome Pathway.Concurrent antitumor and bone-protective effects of everolimus in osteotropic breast cancer.Novel strategies for anti-aging drug discovery.mTOR Signaling in Growth, Metabolism, and Disease.Energetic interventions for healthspan and resiliency with aging.Nutrition and energetics in rodent longevity research.Peptidylprolyl Isomerases as In Vivo Carriers for Drugs That Target Various Intracellular Entities.Restoration of metabolic health by decreased consumption of branched-chain amino acids.Cardioprotective effects of dietary rapamycin on adult female C57BLKS/J-Leprdb mice.Effects of rapamycin on growth hormone receptor knockout mice.Autophagy promotes MSC-mediated vascularization in cutaneous wound healing via regulation of VEGF secretion.mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review.Intermittent mTOR inhibition reverses kidney aging in old rats.A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects.Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice.Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms.β-Cell Autophagy in Diabetes Pathogenesis.Rapamycin rescues BMP mediated midline craniosynostosis phenotype through reduction of mTOR signaling in a mouse model mTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases

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P2860

Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system.

http://www.wikidata.org/entity/Q34497857

description

2015 nî lūn-bûn

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2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

@ast

Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

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Alternative rapamycin treatmen ...... ostasis and the immune system.

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Cassidy P Pumper

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Emma L Baar

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Faizan A Syed

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Harpreet K Brar

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Joshua C Neuman

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Michelle E Kimple

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Nicole E Cummings

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Sebastian I Arriola Apelo

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P2860

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism

mTOR is a key modulator of ageing and age-related disease

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

Rapalogs and mTOR inhibitors as anti-aging therapeutics

Correct homeostasis model assessment (HOMA) evaluation uses the computer program

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression

Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2)

Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

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10.1111/ACEL.12405

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1

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15

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Dudley W Lamming

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2015-10-13T00:00:00Z

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