Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation. - Wikidata - awgldk - TriplyDB

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

http://www.wikidata.org/entity/Q34499590

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Building a ninefold symmetrical barrel: structural dissections of centriole assembly p53 protects against genome instability following centriole duplication failure The PLK4-STIL-SAS-6 module at the core of centriole duplication Asterless is required for centriole length control and sperm development DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6.The Centrioles, Centrosomes, Basal Bodies, and Cilia of Drosophila melanogaster.Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay The centrosome and its duplication cycle DAPPER: a data-mining resource for protein-protein interactions STIL binding to Polo-box 3 of PLK4 regulates centriole duplication Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication.Conserved molecular interactions in centriole-to-centrosome conversion.The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans.CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis Suppression of ectopic assembly of centriole proteins ensures mitotic spindle integrity Myt1 inhibition of Cyclin A/Cdk1 is essential for fusome integrity and premeiotic centriole engagement in Drosophila spermatocytes.Drosophila Ana1 is required for centrosome assembly and centriole elongation.A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4 A yeast two-hybrid approach for probing protein-protein interactions at the centrosome.Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging.Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos.A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation.Binding of STIL to Plk4 activates kinase activity to promote centriole assembly Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles.NEK7 is required for G1 progression and procentriole formation.Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse.CEP295 interacts with microtubules and is required for centriole elongation Plk4-dependent phosphorylation of STIL is required for centriole duplication.A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis.The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.Two-step phosphorylation of Ana2 by Plk4 is required for the sequential loading of Ana2 and Sas6 to initiate procentriole formation.Building the right centriole for each cell type.Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis.PLK4: a link between centriole biogenesis and cancer.Once and only once: mechanisms of centriole duplication and their deregulation in disease.Novel STIL Compound Heterozygous Mutations Cause Severe Fetal Microcephaly and Centriolar Lengthening.PLK4 phosphorylation of CP110 is required for efficient centriole assembly.A homeostatic clock sets daughter centriole size in flies.An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly.

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P2860

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

http://www.wikidata.org/entity/Q34499590

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@ast

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@en

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@nl

type

label

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@ast

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@en

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@nl

prefLabel

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@ast

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@en

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@nl

P1433

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P2860

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P356

J.CUB.2014.08.061

P1433

Current Biology

P1476

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation.

@en

P2093

George Tzolovsky

http://www.w3.org/2001/XMLSchema#string

Michal Dadlez

http://www.w3.org/2001/XMLSchema#string

Sandra Schneider

http://www.w3.org/2001/XMLSchema#string

P2860

The Polo kinase Plk4 functions in centriole duplication

Asterless is a scaffold for the onset of centriole assembly

Cep97 and CP110 suppress a cilia assembly program

Genes required for mitotic spindle assembly in Drosophila S2 cells

Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle

Structures of SAS-6 suggest its organization in centrioles

Structural Basis of the 9-Fold Symmetry of Centrioles

Centrioles, centrosomes, and cilia in health and disease

Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells.

Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP.

P304

2526-2532

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scholarly article

P356

10.1016/J.CUB.2014.08.061

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P407

P433

21

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P478

24

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P50

Zoltan Lipinszki

Nikola S Dzhindzhev

P577

2014-09-25T00:00:00Z

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P5875

266079444

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P698

25264260

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

4229625

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