Clinical correlates of NRAS and BRAF mutations in primary human melanoma. - Wikidata - awgldk - TriplyDB

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

http://www.wikidata.org/entity/Q34500495

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NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo Melanoma: from melanocyte to genetic alterations and clinical options Somatic DNA mutation analysis in targeted therapy of solid tumours Melanoma: oncogenic drivers and the immune system Beyond BRAF: where next for melanoma therapy?NRAS mutation status is an independent prognostic factor in metastatic melanoma.Impact of MET expression on outcome in BRAF(V600E/K) advanced melanoma.BRAF-V600 mutations have no prognostic impact in stage IV melanoma patients treated with monochemotherapy Function and Clinical Implications of Long Non-Coding RNAs in Melanoma.Correlation of somatic mutations and clinical outcome in melanoma patients treated with Carboplatin, Paclitaxel, and sorafenib Molecular alterations in clinical stage III cutaneous melanoma: Correlation with clinicopathological features and patient outcome.Variation of mutant allele frequency in NRAS Q61 mutated melanomas.Treatment of NRAS-mutated advanced or metastatic melanoma: rationale, current trials and evidence to date CXCR4 pathway associated with family history of melanoma.New strategies in melanoma: molecular testing in advanced disease.PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.Clinical development of dabrafenib in BRAF mutant melanoma and other malignancies.Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations The prognostic value of BRAF mutation in colorectal cancer and melanoma: a systematic review and meta-analysis.Molecular characterization and patient outcome of melanoma nodal metastases and an unknown primary site.Association between BRAFV600E and NRASQ61R mutations and clinicopathologic characteristics, risk factors and clinical outcome of primary invasive cutaneous melanoma.Driver mutations in melanoma: lessons learned from bench-to-bedside studies Automated universal BRAF state detection within the activation segment in skin metastases by pyrosequencing-based assay U-BRAF(V600)Genotyping of cutaneous melanoma.KIT, NRAS and BRAF mutations in sinonasal mucosal melanoma: a study of 56 cases Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.BRAF, KIT and NRAS mutations and expression of c-KIT, phosphorylated extracellular signal-regulated kinase and phosphorylated AKT in Japanese melanoma patients.Analysis of BRAF and NRAS Mutation Status in Advanced Melanoma Patients Treated with Anti-CTLA-4 Antibodies: Association with Overall Survival?Association Between NRAS and BRAF Mutational Status and Melanoma-Specific Survival Among Patients With Higher-Risk Primary Melanoma.Somatic and germline analyses of a long term melanoma survivor with a recurrent brain metastasis.Association of activated c-Met with NRAS-mutated human melanomas.Molecular characterization of a selected cohort of patients affected by pulmonary metastases of malignant melanoma: Hints from BRAF, NRAS and EGFR evaluation.Tumor cellularity as a quality assurance measure for accurate clinical detection of BRAF mutations in melanoma.Revisiting determinants of prognosis in cutaneous melanoma.A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma Targeting mutant NRAS signaling pathways in melanoma.Molecular targets in melanoma: time for 'ethnic personalization'Molecular targeted therapies in metastatic melanoma.Immunotherapy in the management of melanoma: current status.Established and Emerging Biomarkers in Cutaneous Malignant Melanoma.

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P2860

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

http://www.wikidata.org/entity/Q34500495

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@ast

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@en

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

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type

label

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@ast

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@en

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@nl

prefLabel

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@ast

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@en

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@nl

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1078-0432.CCR-10-2276

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Clinical Cancer Research

P1476

Clinical correlates of NRAS and BRAF mutations in primary human melanoma.

@en

P2093

Carla L Warneke

http://www.w3.org/2001/XMLSchema#string

Carolyn P Cooke

http://www.w3.org/2001/XMLSchema#string

Elizabeth A Grimm

http://www.w3.org/2001/XMLSchema#string

Jeffrey E Gershenwald

http://www.w3.org/2001/XMLSchema#string

Julie A Ellerhorst

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Li-E Wang

http://www.w3.org/2001/XMLSchema#string

Marcella M Johnson

http://www.w3.org/2001/XMLSchema#string

Qingyi Wei

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Suhendan Ekmekcioglu

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Victor G Prieto

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P2860

Mutations of the BRAF gene in human cancer

Final version of 2009 AJCC melanoma staging and classification

Distinct sets of genetic alterations in melanoma

BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma.

NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.

Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma

High frequency of BRAF mutations in nevi.

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

Detection of B-RAF and N-RAS mutations in human melanoma.

Activating BRAF and N-Ras mutations in sporadic primary melanomas: an inverse association with allelic loss on chromosome 9.

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229-235

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scholarly article

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10.1158/1078-0432.CCR-10-2276

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2

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17

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2010-10-25T00:00:00Z

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20975100

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3022950

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