N-ras mutations in human cutaneous melanoma from sun-exposed body sites. - Wikidata - awgldk - TriplyDB

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

http://www.wikidata.org/entity/Q36770363

about

msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation Preponderance of the oncogenic V599E and V599K mutations in B-raf kinase domain is enhanced in melanoma cutaneous/subcutaneous metastases Current State of Animal (Mouse) Modeling in Melanoma Research Cross-species models of human melanoma Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo.pMD-Membrane: A Method for Ligand Binding Site Identification in Membrane-Bound Proteins Correlation of somatic mutations and clinical outcome in melanoma patients treated with Carboplatin, Paclitaxel, and sorafenib What are we learning from the cancer genome?Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.Clinical correlates of NRAS and BRAF mutations in primary human melanoma.Novel Ras antagonist blocks human melanoma growth.Superficial spreading and nodular melanoma are distinct biological entities: a challenge to the linear progression model.Vemurafenib: a new treatment for BRAF-V600 mutated advanced melanoma.Vertical targeting of the phosphatidylinositol-3 kinase pathway as a strategy for treating melanoma.Role of proto-oncogene activation in carcinogenesis.Cooperative effects of INK4a and ras in melanoma susceptibility in vivo.BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs.BRAF in Melanoma: Pathogenesis, Diagnosis, Inhibition, and Resistance Mutations in ras genes in cells cultured from mouse skin tumors induced by ultraviolet irradiation.Molecular characterisation of pancreatic ductal adenocarcinoma in patients under 40.Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma Activated ras. Yet another player in melanoma?Induction of different morphologic features of malignant melanoma and pigmented lesions after transformation of murine melanocytes with bFGF-cDNA and H-ras, myc, neu, and E1a oncogenes.No N-ras mutations in human uveal melanoma: the role of ultraviolet light revisited.Delving into somatic variation in sporadic melanoma.The melanomas: a synthesis of epidemiological, clinical, histopathological, genetic, and biological aspects, supporting distinct subtypes, causal pathways, and cells of origin.Targeting drivers of melanoma with synthetic small molecules and phytochemicals.Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104)Applications of genomics in melanoma oncogene discovery Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site.NRAS and EPHB6 mutation rates differ in metastatic melanomas of patients in the North Island versus South Island of New Zealand.Combination therapies for the treatment of advanced melanoma: a review of current evidence.Resistance to transforming growth factor β-mediated tumor suppression in melanoma: are multiple mechanisms in place?Molecular testing in melanoma.Distinct dynamics and interaction patterns in H- and K-Ras oncogenic P-loop mutants.Molecular characterisation of cutaneous melanoma: creating a framework for targeted and immune therapies.The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma.Potential therapeutic targets of epithelial-mesenchymal transition in melanoma.Genes involved in cell cycle G1 checkpoint control are frequently mutated in human melanoma metastases

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P2860

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

http://www.wikidata.org/entity/Q36770363

description

1989 nî lūn-bûn

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1989年の論文

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1989年論文

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1989年論文

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1989年論文

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1989年論文

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1989年論文

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1989年论文

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1989年论文

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1989年论文

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name

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

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N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

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type

label

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

@ast

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

@en

prefLabel

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

@ast

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

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Molecular and Cellular Biology

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N-ras mutations in human cutaneous melanoma from sun-exposed body sites

@en

P2093

A J Boot

http://www.w3.org/2001/XMLSchema#string

B M Burgering

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D J Ruiter

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J L Bos

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L J van 't Veer

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P I Schrier

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S Osanto

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P2860

Activation of N-ras in a human melanoma cell line

Genetic alterations during colorectal-tumor development

Detection of a low frequency of activated ras genes in human melanomas using a tumorigenicity assay

The specificity of UV-induced mutations at an endogenous locus in mammalian cells.

Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction.

Molecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient.

The ras gene family and human carcinogenesis.

Solar exposure in the etiology of cutaneous melanoma.

KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas.

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7

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9

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Rogier Versteeg

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2674680

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362784

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