APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway.
about
Adiponectin signaling and function in insulin target tissuesAdiponectin, driver or passenger on the road to insulin sensitivity?APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments.A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac diseaseAdiponectin stimulates lipid metabolism via AMPK in rabbit blastocysts.Obesity, inflammation, and lung injury (OILI): the good.Adiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial DysfunctionMetabolic influences on reproduction: adiponectin attenuates GnRH neuronal activity in female miceAdiponectin receptor 1 C-terminus interacts with PDZ-domain proteins such as syntrophins.Adiponectin impairs chicken preadipocytes differentiation through p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathwaysAPPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling.Adiponectin action: a combination of endocrine and autocrine/paracrine effects.Adiponectin increases skeletal muscle mitochondrial biogenesis by suppressing mitogen-activated protein kinase phosphatase-1.Phosphorylation of adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain, and leucine zipper motif 1 (APPL1) at Ser430 mediates endoplasmic reticulum (ER) stress-induced insulin resistance in hepatocytesMetabolic function of the CTRP family of hormones.Adipokines and the female reproductive tract.Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis.Endosomal crosstalk: meeting points for signaling pathways.Regulation of adiponectin multimerization, signaling and function.Adiponectin Promotes Human Jaw Bone Marrow Stem Cell Osteogenesis.Distinct Roles for APPL1 and APPL2 in Regulating Toll-like Receptor 4 Signaling in Macrophages.p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development.Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways.Adiponectin decreases lipids deposition by p38 MAPK/ATF2 signaling pathway in muscle of broilers.Recombinant globular adiponectin inhibits lipid deposition by p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathways in chicken adipocytes.Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms.APPL1 transgenic mice are protected from high-fat diet-induced cardiac dysfunction.
P2860
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P2860
APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@ast
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@en
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@nl
type
label
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@ast
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@en
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@nl
prefLabel
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@ast
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@en
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@nl
P2093
P2860
P1476
APPL1 mediates adiponectin-sti ...... he TAK1-MKK3-p38 MAPK pathway.
@en
P2093
Caleb M Reyes
Lijun Zhou
Lily Q Dong
Xiaoban Xin
P2860
P304
P356
10.1152/AJPENDO.00427.2010
P577
2010-10-26T00:00:00Z