Basic tetrapeptides as potent intracellular inhibitors of type A botulinum neurotoxin protease activity.
about
Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165Cleavage of SNAP25 and its shorter versions by the protease domain of serotype A botulinum neurotoxin.Cargo-delivery platforms for targeted delivery of inhibitor cargos against botulism.Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discoveryInhibition of catalytic activities of botulinum neurotoxin light chains of serotypes A, B and E by acetate, sulfate and calcium.The C terminus of the catalytic domain of type A botulinum neurotoxin may facilitate product release from the active siteMolecular structures and functional relationships in clostridial neurotoxins.Targeting bacterial toxins.Current strategies for designing antidotes against botulinum neurotoxins.Challenges in searching for therapeutics against Botulinum Neurotoxins.Tyrosine phosphorylation of botulinum neurotoxin protease domainsGlycine insertion at protease cleavage site of SNAP25 resists cleavage but enhances affinity for botulinum neurotoxin serotype A.
P2860
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P2860
Basic tetrapeptides as potent intracellular inhibitors of type A botulinum neurotoxin protease activity.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@ast
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@en
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@nl
type
label
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@ast
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@en
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@nl
prefLabel
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@ast
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@en
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@nl
P2093
P2860
P356
P1476
Basic tetrapeptides as potent ...... neurotoxin protease activity.
@en
P2093
George Oyler
Martha Hale
S Ashraf Ahmed
Subramanyam Swaminathan
P2860
P304
P356
10.1074/JBC.M110.146464
P407
P577
2010-10-20T00:00:00Z